Current trends and future perspectives of dental pulp capping materials: A systematic review

Abstract

To systematically review the literature to analyze the current trends and future perspectives of dental pulp capping materials through an analysis of scientific and technological data. This study is reported in accordance with the PRISMA Statement. Nine databases were screened: PubMed (MedLine), Lilacs, IBECS, BBO, Web of Science, Scopus, SciELO, Google Scholar, and The Cochrane Library. Additionally, the following patent applications were searched online in Questel Orbit (Paris, France), USPTO, EPO, JPO, INPI, and Patentscope databases. A total of 716 papers and 83 patents were included. Calcium hydroxide was the main type of material studied, especially for direct pulp capping, followed by MTA. Patents related to adhesives or resins increased from 1998 e 2008, while in the last years, a major increase was observed in bioactive materials (containing bioactive proteins), materials derived from MTA (calcium silicate, calcium phosphate and calcium aluminate-based cements) and MTA. It was possible to obtain a scientific and technological overview of pulp capping materials. MTA has shown favorable results in vital pulp therapy that seem to surpass the disadvantages of calcium hydroxide. Recent advances in bioactive materials and those derived from MTA have shown promising results that could improve biomaterials used in vital pulp treatments. © 2017 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 106B: 1358-1368, 2018.

Is a calcium hydroxide liner necessary in the treatment of deep caries lesions? A systematic review and meta‐analysis

“…, Da Rosa et al . ). However, a good marginal seal is paramount to prevent bacterial substrate infiltrating into the dentine and to control caries progression (Falster et al .…”

“…It should also be emphasized the necessity of using a liner directly on permanent pulp tissue, since it is a completely different clinical condition and there is no dentine barrier (Da Rosa et al . ).…”

“…, Da Rosa et al . ). The purpose of using a liner is to promote the formation of a dentine bridge and tertiary dentine to protect pulp tissue from thermal and electrical stimuli, or chemical agents leached from adhesive systems (Schwendicke et al .…”

Disclosing the physiology of pulp tissue for vital pulp therapy

“…They have improved properties compared to MTA, such as good sealing correlated to expansion, being able to set in the presence of fluids, releasing ions such as calcium and having good biological properties (Da Rosa et al 2017). They have improved properties compared to MTA, such as good sealing correlated to expansion, being able to set in the presence of fluids, releasing ions such as calcium and having good biological properties (Da Rosa et al 2017).…”

“…Some studies have suggested that the effect of using calcium hydroxide or glass-ionomer cement on dentine caries is not superior to the use of an inert material (such as wax; Corralo & Maltz 2013), in indirect pulp capping of primary (Marchi et al 2006, Casagrande et al 2010, Schwendicke et al 2015 or permanent teeth (Baratieri et al 2002, Whitworth et al 2005, Wegehaupt et al 2009, Pereira et al 2017). Hence, there is an ongoing quest to find pulp capping agents that have improved physico-mechanical properties, and potentiate the best biological response (Da Rosa et al 2017). Hence, there is an ongoing quest to find pulp capping agents that have improved physico-mechanical properties, and potentiate the best biological response (Da Rosa et al 2017).…”