Sclerotic Regressing Large Congenital Nevus

Abstract

Regression of congenital nevi is usually associated with loss of pigment or halo formation. In rare cases, regression is characterized by sclerosis and hair loss. We describe a rare case of a sclerotic hypopigmented large congenital melanocytic nevus in which a localized scleroderma-like reaction process of regression seemed to have started in utero and progressed throughout early childhood.

Final congenital melanocytic naevi colour is determined by normal skin colour and unaltered by superficial removal techniques: a longitudinal study

“…This phenomenon could have major implications for cosmetic surgery decisions taken at or near birth. Spontaneous lightening should be distinguished from the very rare cases of actual regression of the naevus . It should also be noted that a small percentage of CMN are tardive, defined as appearing fully or partially after birth.…”

“…Spontaneous lightening should be distinguished from the very rare cases of actual regression of the naevus. [11][12][13][14][15][16][17][18][19][20][21][22] It should also be noted that a small percentage of CMN are tardive, defined as appearing fully or partially after birth. These are the only naevi in our experience that appear to darken after birth, although they are, in fact, only developing their full phenotype.…”