Sclerosing stromal tumor of the ovary: radiologic findings

Abstract

Sclerosing stromal tumor is a rare ovarian neoplasm. We describe the radiologic findings of sclerosing stromal tumor in two patients. In both patients, MR and CT images showed a large mass in the left adnexal region. On dynamic contrast-enhanced images, the tumors showed early peripheral enhancement with centripetal progression.

Sclerosing stromal tumor of the ovary in a premenarchal female

“…The thick peripheral rim present on US and CT histologically comprises cellular areas patterned in a nodular configuration, separated by edematous stroma with prominent vasculature. Although MRI was not performed in this case, two recent reports suggest that MR and dynamic MR findings may be more specific in differentiating this benign ovarian neoplasm from a malignant neoplasm [3,6].…”

“…[3,6]. Both the US and CT findings suggested a complex cystic mass with marked peripheral vascularity, characteristics often associated with malignant ovarian neoplasms.…”

“…Computed tomography (CT), magnetic resonance imaging (MRI), and ultrasound findings have been recently described [3,6] for post-menarchal women, but have not been reported previously in the pediatric radiology literature. We present a case of SST in a 10-year-old, pre-menarchal female, the youngest patient reported in the literature to date, and we describe its appearance on sonography and computed tomography with pathologic correlation.…”

“…Unlike the thecoma-fibroma group of ovarian stromal tumors, which tend to occur in the fifth and sixth decades, the SST predominantly affects young women with a mean age of 28 years [1,2,3,4,5,6,7]. Following the original description of the tumor in 1973 by Chalvardjian and Scully, in their series of 10 patients [1], there have been several additional small series reported [2,5] and multiple isolated case reports focusing on the pathologic aspects of this unusual entity [3]. To our knowledge, all of the affected patients described in the reported series were 14 years or older and post-menarchal.…”

CT findings of sclerosing stromal tumor of the ovary: A report of two cases and review of the literature

“…In a previous study, the cellular areas were observed to be composed of oval to spindle-shaped cells, with a single oval to round-shaped nucleus and a single prominent nucleolus (8). In addition, the cytoplasm was moderately abundant, eosinophilic and occasionally vacuolated (8).…”