Sclerosing Hemangioma (Pneumocytoma) of the Lung: An Analysis of 8 Cases

Abstract

Objective: We aimed to evaluate clinical manifestations, radiological findings, treatment, and outcomes of pulmonary sclerosing hemangioma (SH). Methods:We retrospectively reviewed eight cases of pulmonary sclerosing hemangioma diagnosed at our institution from January 2006 to April 2014. Their demografic findings, symptoms, radiological appearences, diagnostic methods, treatments and surveys were recorded.Results: There were four female and four male patients. The age at the time of diagnosis ranged from 23 to 79 years, with a mean age of 56.1 years. Two patients were asymptomatic. Among six symptomatic patients, hemoptysis was the most frequent symptom. The radiological feature was a solitary nodule or mass in seven cases. In the remaining case, there were multiple distinct masses and nodules in bilateral lung fields. The tumor involved lung parenchyma in seven cases and endobronchially located in the remaining patient. Seven patients with parenchymal location underwent surgery. Wedge resection was the most common surgical procedure. Diagnosis of SH was established by surgical biopsy in seven cases and by bronchoscopic biopsy in one case. The most common histological pattern was solid pattern. During the follow-up ranging from 2 months to 76 months, seven cases who underwent surgery had an excellent prognosis with no evidence of recurrence. The patient with multiple lesions died one month after diagnosis. Conclusion:SH of the lung is a rare tumor. Surgical resection usually requires for both diagnosis and treatment of this tumor. The patients had excellent prognosis with no evidence of recurrence following surgery.

Sclerosing Pneumocytoma: A Ten-Year Experience at a Western Balkan University Hospital

“…The maximum diameters of SP in our patients varied from 1 to 2.5 cm. According to other studies, lesions range from 0.3 to 7 cm in greatest dimension [2,4,6]. Some authors have assumed that clinical symptoms can be evident due to enlargement and consequent pressure on adjacent lung parenchyma.…”

“…Although its name implicated a vascular neoplasm, further studies have reported the possible pulmonary epithelium (pneumocyte type II) origin of this tumor. This conclusion has been strongly supported by immunohistochemical findings, and that is why alternative terms, such as pneumocytoma, sclerosing pneumocytoma, or papillary pneumocytoma, have been suggested [2]. In the newest World Health Organization (WHO) classification of lung and pleural tumors from 2015, it has been classified under the more convenient name pneumocytoma [3].…”

Case Report: Rare Case of Pneumocytoma

“…The maximum diameter of the pneumocytoma in our patient was >7 cm. According to other studies, lesions range from 0.3 to 7 cm in greatest dimension [2,12,5,6]. Some authors have assumed that clinical symptoms can be evident due to enlargement and consequent pressure on adjacent lung parenchyma.…”

“…Although its name implicated a vascular neoplasm, further studies have reported the possible pulmonary epithelium (pneumocyte type II) origin of this tumor. This conclusion has been strongly supported by immunohistochemical findings, and that is why alternative terms, such as pneumocytoma, sclerosing pneumocytoma, or papillary pneumocytoma, have been suggested [2], [3]. In the newest World Health Organization (WHO) classification of lung and pleural tumors from 2015, it has been classified under the more convenient name pneumocytoma [4[, [3].…”

A Case of Sclerosing Pneumocytoma: A Rare Lung Tumor

“…Immunohistochemically, round stromal cells were TTF-1 and EMA (+), and pancytokeratin (-). The surface epithelium was TTF-1, EMA, and pancytokeratin (+), and CEA, S100, smooth muscle actin, chromogranin-a, and CD34 negative (2,7,13). Vascular tumors, carcinoid tumor, and pulmonary hamartoma were considered in the discriminative diagnosis.…”