Sclérœdème de Buschke chez un diabétique : traitement par immunoglobulines intraveineuses

Barde, C.; Masouyé, Isabelle; Saurat, J.‐H.; Gál, Felix

doi:10.1016/j.annder.2008.09.024

Cited by 18 publications

(4 citation statements)

References 14 publications

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“…41 Mobility is reduced and may lead to a restrictive respiratory syndrome due to the skin thickening. 42 The affected area is painless and can present decreased sensitivity to touch. 41 Visceral involvement is rare, affecting eyes, tongue, pharynx, esophagus, musculoskeletal tissue, joints, heart (pericardial and pleural effusion) and hepatosplenomegaly.…”

Section: Sclerodermiform Disordersmentioning

confidence: 99%

“…41 Visceral involvement is rare, affecting eyes, tongue, pharynx, esophagus, musculoskeletal tissue, joints, heart (pericardial and pleural effusion) and hepatosplenomegaly. 40 , 42 , 43…”

Section: Sclerodermiform Disordersmentioning

confidence: 99%

“…cyclosporine and methotrexate), pentoxifylline, prostaglandin E1, intravenous immunoglobulin, penicillamine, antibiotics, systemic corticosteroids, and intralesional, factor XIII, aminobenzoate, colchicine and DMSO gel, radiotherapy, photochemotherapy with psoralen and ultraviolet A (PUVA), and recently, tamoxifen and irradiation with electron beam. 36 , 41 , 42 , 50 , 59 , 60 The therapy may be effective, probably due to the upregulation of collagenase synthesis by fibroblasts and subsequent degradation of collagen fibers. 33 , 60 , 61 …”

Section: Sclerodermiform Disordersmentioning

confidence: 99%

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Diabetes mellitus and the skin

Mendes¹,

Miot²,

Haddad³

2017

An. Bras. Dermatol.

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Several dermatoses are routinely associated with diabetes mellitus, especially in patients with chronic disease. This relationship can be easily proven in some skin disorders, but it is not so clear in others. Dermatoses such necrobiosis lipoidica, granuloma annulare, acanthosis nigricans and others are discussed in this text, with an emphasis on proven link with the diabetes or not, disease identification and treatment strategy used to control those dermatoses and diabetes.

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Section: Sclerodermiform Disordersmentioning

confidence: 99%

“…41 Visceral involvement is rare, affecting eyes, tongue, pharynx, esophagus, musculoskeletal tissue, joints, heart (pericardial and pleural effusion) and hepatosplenomegaly. 40 , 42 , 43…”

Section: Sclerodermiform Disordersmentioning

confidence: 99%

Section: Sclerodermiform Disordersmentioning

confidence: 99%

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Diabetes mellitus and the skin

Mendes¹,

Miot²,

Haddad³

2017

An. Bras. Dermatol.

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“…Recently, multiple reports had described intravenous immunoglobulin (IVIg) therapy especially in postinfectious, diabetic, and monoclonal gammopathy-associated scleredema that were refractory to more standard therapies with better efficacy. 7 In our patient diabetes was one of the predisposing risk factor. We have ruled out monoclonal gammopathy and myeloma in our case as bone marrow biopsy was suggestive of 4% plasma cells and reactive marrow.…”

Section: Discussionmentioning

confidence: 56%

Scleredema — Rare skin manifestation in diabetic

Nimbolkar¹,

Thacker

Gandhi³

2022

SAJCRR

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Scleredema is a connective tissue disorder of unknown etiology. A 44 years diabetic, obese female patient, admitted with edema feet, erythematous, indurated hyper pigmentation with ascending progression to trunk which rapidly transformed to painless dark pigmented blister and hard non-pitting edema of anterior abdominal wall. In a week time. She was managed with broad spectrum antibiotics, was aggressively diuresed along with albumin infusion. Her skin biopsy was done which revealed scleredema. She had poor LV function due to volume overload or cardiomyopathy. After initial improvement on 14 day, she suddenly developed fulminant septicemia. Within hours, she displayed multi organ dysfunction and the heart and kidney which were already delicately balanced, decompensated. There was intractable arrhythmias and severe LV dysfunction, renal failure and ischemic hepatitis following severe hypotension. Scleredema in diabetic subjects, can be an ominous sign for producing fulminant multiorgan dysfunction and can present as cardiomyopathy, myocarditis, liver dysfunction etc., and these patients are more prone to infections or may be vice versa. Scleredema can be considered as a marker of fulminant illness in immunocompromised individuals. There is a need for treatment protocols or research into this a rather enigmatic but rare illness.

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