Scleredema adultorum of Buschke over an unusual site associated with pregnancy

Abstract

Scleredema adultorum of Buschke is characterized by symmetrical, diffuse, non-pitting erythematous swelling of the skin due to accumulation of collagen and mucopolysaccharides in the dermis. Herein we report a case of scleredema over an unusual site in a pregnant woman.

Concurrent Scleredema and Pyoderma Gangrenosum: Case Report and Review of Comorbid Conditions

“…However, comorbidities outside of these three types have also been observed in patients with scleredema; comorbid conditions are summarized in Table 1 [1,[5][6][7][8][9][10]. Some of the conditions include thyroid disease (hyperthyroidism), autoimmune disorders (Sjogren syndrome), and malignancy [8,9].…”

“…A biopsy of the affected skin on her thigh showed pathologic features of scleredema and she was treated with amoxicillin-clavulanic acid for two weeks. Her scleredema resolved three months after delivery [ 10 ].…”

“…Both diseases can be associated with monoclonal gammopathy [ 3 , 14 ]. Single patients with other conditions in common include pregnancy and chronic myeloid leukemia [ 9 , 10 , 16 , 18 ]. Diabetes has also been described in pyoderma gangrenosum patients; however, this may be a coincidental finding and not related to neutrophilic dermatosis [ 17 ].…”

Post-streptococcal scleredema an unusual rare mimicker of scleroderma: a case report

“…The plan is to administer him immunoglobulin intravenously if he doesn't regain his normal skin elasticity after one year of follow-up. n DISCUSSION Scleredema of Buschke is a rare skin condition that is characterized by thickening and hardening of the skin (6). It is typically caused by a streptococcal infection, such as strep throat or scarlet fever, and can occur in individuals of any age (7).…”