Schwannoma of the nasal cavity: A case report and a review

Mosalleum, E.; Phillips, V M

doi:10.4103/1858-5000.157509

Cited by 7 publications

(14 citation statements)

References 12 publications

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“…Mitra B et al [2] , Vaidya MM et al [3] , Dhawle MS et al [4] and Mangubat EZ et al [6] documented schwannoma in male patient. On the contrary, Singh M et al [5] , Mosalleum EMA [7] and Wong E et al [8] reported the lesion in female patients in their case reports.…”

Section: Discussionmentioning

confidence: 93%

“…Wong E et al [8] reported a case of giant primary schannoma involving left nasal cavity and ethmoidal sinus. In contrast, Mosalleum EMA [7] et al documented the neoplasm involving left nasal vestibule without any involvement of paranasal sinues. Mitra B et al [2] also described a case of schwannoma arising from left side of nasal septum without involving paranasal sinuses.…”

Section: Discussionmentioning

confidence: 94%

“…The cells have cigar-shaped nuclei and perinuclear halo. [7] In contrast to other lesion, Schwannoma shows characteristic histopathological features. [4] Neurofibromas are positive for S-100, EMA and NF.…”

Section: Discussionmentioning

confidence: 99%

“…Vaidya MM et al [3] , Dhawle MS et al [4] , Mangubat EZ et al [6] , Mosalleum EMA [7] et al documented the tumor in fourth decade. Singh M et al [5] observed the lesion in fifth decade.…”

Section: Discussionmentioning

confidence: 99%

“…Neurofibroma is a benign peripheral nerve tumor composed of Schwann cells, perineural cells and intra-neural fibroblast. [7] Residual axons are often present within the tumor. Unlike, Schwannoma, blood vessels in neurofibroma generally lack hyalinization.…”

Section: Discussionmentioning

confidence: 99%

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Right Ethmoidal Sinus Schwannoma: Case Report of a Common Entity with an Unusual Presentation

Kavitha

Swapna

Kumarguru

et al. 2020

Ann of Pathol and Lab Med

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Schwannomas are benign, encapsulated nerve sheath tumors arising from Schwann cells. Approximately, 25-40% of all Schwannomas occur in the head and neck region, acoustic nerve being the most frequent site. The tumors originating from nasal cavity or paranasal sinuses are rare and constitutes only four percent. A 40-year-old male presented with history of blurred vision of right eye and protrusion of right eye ball since 6 months. It was associated with history of watering and redness. Examination of right eye revealed mild proptosis and ptosis. Computed Tomography [CT] scan showed a large expansile cystic lesion measuring about 5.2x5.6x6.5cm involving entire right ethmoidal sinus. It showed expansion into anterior cranial fossa, roof and medial wall of right orbit. Radiological opinion suggested mucocele of right ethmoidal sinus. Intra-operatively, tissue specimen was sent for squash smear cytology. Cytology smears showed features suggestive of spindle cell tumor. Possibility of Schwannoma was considered. The specimen was subsequently subjected to histopathological examination. Microscopy showed tumor tissue composed of tumor cells arranged in alternate hypercellular and hypocellular pattern. Hypercellular areas showed occasional verocay bodies. Hypocellular areas showed loosely arranged spindle shaped tumor cells. Histopathological features were suggestive of Schwannoma. On Immunohistochemistry (IHC), neoplastic cells were positive for S-100 and negative for EMA. Ethmoidal sinus schwannoma extending into anterior cranial fossa is an unusual presentation. Clinically, it poses a diagnostic dilemma. Squash smear cytology is challenging, but helpful in establishing the correct diagnosis. Histopathology is confirmatory and immunohistochemistry is supportive.

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Section: Discussionmentioning

confidence: 93%

Section: Discussionmentioning

confidence: 94%

Section: Discussionmentioning

confidence: 99%

“…Vaidya MM et al [3] , Dhawle MS et al [4] , Mangubat EZ et al [6] , Mosalleum EMA [7] et al documented the tumor in fourth decade. Singh M et al [5] observed the lesion in fifth decade.…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 3 more Smart Citations

Right Ethmoidal Sinus Schwannoma: Case Report of a Common Entity with an Unusual Presentation

Kavitha

Swapna

Kumarguru

et al. 2020

Ann of Pathol and Lab Med

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Extracranial Schwannomas of the Head and Neck: A Literature Review and Audit of Diagnosed Cases Over a Period of Eight Years

Phulware

Sardana

Chauhan

et al. 2022

Head and Neck Pathol

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Two cases of neurilemmoma in the nasal vestibule

Heo¹,

Kim²,

Kim³

2022

Medicine

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Rationale:Neurilemmoma is a benign tumor derived from the Schwann cells of the nerve sheath. The highest incidence of neurilemmoma occurs in the head and neck region; however, the nose and paranasal sinuses are rarely involved. Less than 4% of these tumors involve the nasal cavity and paranasal sinuses. To date, only six cases of nasal vestibule neurilemmoma have been reported.Patient concerns:Two patients (a 32-year-old man and a 42-year-old woman) visited our clinic with complaint of a lump in the left nasal vestibule.Diagnosis:Histopathological examination and immunohistochemical staining confirmed a neurilemmoma.Interventions:The mass was completely removed via an intranasal approach.Outcomes and Lessons:Neurilemmoma is easy to overlook because it occurs rarely in the nasal vestibule, but neurilemmoma needs to be considered as a differential diagnosis.

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Schwannoma of the nasal cavity: A case report and a review

Cited by 7 publications

References 12 publications

Right Ethmoidal Sinus Schwannoma: Case Report of a Common Entity with an Unusual Presentation

Right Ethmoidal Sinus Schwannoma: Case Report of a Common Entity with an Unusual Presentation

Extracranial Schwannomas of the Head and Neck: A Literature Review and Audit of Diagnosed Cases Over a Period of Eight Years

Two cases of neurilemmoma in the nasal vestibule

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