Two cases of neurilemmoma in the nasal vestibule

Heo, Sung Jae; Kim, A. Young; Kim, Jung Soo

doi:10.1097/md.0000000000029006

Cited by 3 publications

(3 citation statements)

References 10 publications

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“…Schwannomas are not-so-rare, benign tumors originating from Schwann cells of the nerve sheath 1 . They are also called neurilemmomas or neurinomas.…”

Section: Introductionmentioning

confidence: 99%

“…They are also called neurilemmomas or neurinomas. Twenty-five to forty percent of schwannomas occur in the head and neck region, and only 0.5% to 1% occur in the oral and maxillofacial area 1 , 2 . Although the oral cavity has extensive nervous plexuses, it does not correlate with the number of schwannomas that develop there 3 .…”

Section: Introductionmentioning

confidence: 99%

“…These cells appear as organized streaming fascicles in Antoni A, with areas of palisading nuclear arrangements around eosinophilic amorphous masses known as Verocay bodies. On the other hand, Antoni B areas are relatively paucicellular, with haphazardly arranged Schwann cells in a myxoid or loose stroma 1 , 4 , 6 , 7 . Cystic degeneration, thick hyalinized vessels, hemosiderin deposition, lipid-laden macrophages, and nuclear atypia (degenerative changes) are other features of schwannomas 8 .…”

Section: Introductionmentioning

confidence: 99%

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A rare histopathological variant of Schwannoma with rosette-like arrangements and epithelioid cells: a case report from a histopathologist’s perspective

Mehendiratta,

Sant,

Lakhanpal

et al. 2023

JKAOMS

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Schwannomas exhibit histopathological variation that leads to diagnostic dilemmas, although less frequent in the oral cavity. We describe a case with unique histopathology and no relevant clinical history that adds to the breadth of literature on the diversity presented by Schwannoma. A 60-year-old female patient presented with a small dome-shaped, asymptomatic swelling on the alveolar ridge 6 years in duration. Histopathologically, it showed rich cellular pathology with a unique arrangement of tumor cells forming irregular rosettes. Each rosette presented with a central core of fibrin-collagenous material and the tumor cells were arranged on the periphery, exhibiting epithelioid change with evidence of mild cellular and nuclear pleomorphism. On immunohistochemical evaluation, the cells were strongly and diffusely positive for S-100 and negative for Ki-67. A diagnosis of benign Schwannoma with a rosette-like arrangement with epithelioid change was made. The case report emphasizes the risk of misdiagnosis and the importance of awareness regarding rare histopathological variants of Schwannoma.

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“…Schwannomas are not-so-rare, benign tumors originating from Schwann cells of the nerve sheath 1 . They are also called neurilemmomas or neurinomas.…”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

A rare histopathological variant of Schwannoma with rosette-like arrangements and epithelioid cells: a case report from a histopathologist’s perspective

Mehendiratta,

Sant,

Lakhanpal

et al. 2023

JKAOMS

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A Rare Neurilemmoma of the Nasal Vestibule: A Case With the Review of Literature

Zhou,

Kong,

et al. 2024

Ear Nose Throat J

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A variety of diseases can affect the nasal vestibule. It might be challenging to diagnose and treat a nasal vestibular tumor due to the anatomical characteristics of the nasal vestibule. Neurilemmoma is a tumor derived from Schwann cells of the nerve sheath. Less than 4% of these tumors invade the nasal cavity and sinuses. Nasal vestibule neurilemmoma is rare, it is often overlooked when a mass discovered. The diagnosis of it is mainly based on clinical symptoms, nasal endoscopy, and imaging, The mainstay of treatment is complete resection surgery. Pathological examination provides the final diagnosis. We present a patient with nasal vestibule neurilemmoma who underwent a successful endoscopic surgery without cosmetic deformity, and discuss the clinical manifestations, histological features, imaging features, differential diagnosis, treatment options, then reviewed relevant literature of this rare benign lesion.

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Clinicopathological Findings of Surgically Treated Nasal Cavity Schwannomas: A Case Series

Yaprak Bayrak,

Yaylacı,

Ozturk

2024

Ear Nose Throat J

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Objectives: Nasal cavity schwannomas are exceedingly rare, benign neoplasms that pose challenges in clinical differentiation from other nasal tumors. Methods: This study presents 5 cases of nasal cavity schwannoma treated surgically over a 10 year period, along with a review of the literature. Results: The most prevalent symptoms included unilateral nasal obstruction and intermittent nosebleeds. Tumors originated from various nasal sites, including the septum, middle conchae, lateral nasal wall, and alar mucosa. All surgeries were conducted transnasally, with 3 tumors excised en bloc, and the remaining two subjected to piecemeal resection. Ancient schwannoma was identified in 4 cases. No instances of recurrence were observed during the average 61 month follow-up period. Conclusions: The definitive diagnosis of schwannomas necessitates histopathological examination. An endoscopic approach to the nasal cavity, obviating the need for external intervention, proved highly effective and appropriate for both diagnosis and symptom alleviation.

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Two cases of neurilemmoma in the nasal vestibule

Cited by 3 publications

References 10 publications

A rare histopathological variant of Schwannoma with rosette-like arrangements and epithelioid cells: a case report from a histopathologist’s perspective

A rare histopathological variant of Schwannoma with rosette-like arrangements and epithelioid cells: a case report from a histopathologist’s perspective

A Rare Neurilemmoma of the Nasal Vestibule: A Case With the Review of Literature

Clinicopathological Findings of Surgically Treated Nasal Cavity Schwannomas: A Case Series

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