Schwannoma of the conus medullaris: a rare case

Canbay, Suat; Hastürk, Aşkın Esen; Markoç, Fatma; Çağlar, Şükrü

doi:10.5732/cjc.011.10213

Cited by 6 publications

(6 citation statements)

References 12 publications

(16 reference statements)

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“…Histologically, schwannomas consist of compact cellular lesions. Antoni A (interlacing and cellular fascicles) and Antoni B (less cellular and myxoid) areas, combined with positive uniform S-100 staining characterize the histological appearance of typical schwannomas ( 4 ). Therefore, S-100 immunostaining is extremely useful in the differential diagnosis of schwannoma.…”

Section: Discussionmentioning

confidence: 99%

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Schwannoma with an uncommon anal location

Jing

Tian

2014

Oncology Letters

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Schwannomas are slow-growing mesenchymal neoplasms that arise from Schwann cells with low malignant potential. These uncommon neoplasms are nerve sheath tumors that arise at almost any anatomical site. The majority of schwannomas are benign, and few are malignant. The current study presents the rare case of an anal schwannoma that was successfully treated by surgery; there are few such cases previously reported in the literature. The patient was admitted to hospital following the identification of a mass incidentally. The tumor was so large that it compressed the tissue around it, although no symptoms were caused. The pre-operative clinical diagnosis was inconclusive in this case, and a final diagnosis was established based on radiographic and histopathological examination. The current study aimed to provide a possible differential diagnosis for such anally-located masses.

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Section: Discussionmentioning

confidence: 99%

“…The growth of these masses occasionally causes displacement and compression of the nerve of origin, resulting in clinical signs and symptoms ( 3 ). The tumors can develop in either of the two genders and there is no age predilection ( 4 ). Surgical excision is the treatment of choice for schwannomas ( 3 ).…”

Section: Introductionmentioning

confidence: 99%

Schwannoma with an uncommon anal location

Jing

Tian

2014

Oncology Letters

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“…These schwannomas generally have low to intermediate signal intensity on T1-weighted images. On T2-weighted images, they may be heterogeneous with focal areas of hyperintensity and hypointensity, hemorrhage, and collagen deposition [8]. A well-defined plane of cleavage, intense contrast enhancement, presence of an additional extramedullary component, and thickening of nerve roots are features characteristic but not diagnostic of a schwannoma.…”

Section: Discussionmentioning

confidence: 99%

“…Surgery is the treatment of choice for intraspinal intramedullary schwannomas. As compared to gliomas, schwannomas usually have defined plane of cleavage and it is hence possible to perform a gross total excision [8,10]. In cases with nerve root involvement or dense adhesions to surrounding tissue, subtotal excision is advised to avoid unacceptable surgical complications [1].…”

Section: Discussionmentioning

confidence: 99%

Intramedullary schwannoma of conus medullaris: rare site for a common tumor with review of literature

Singh

Chaturvedi

Pant

et al. 2018

Spinal Cord Ser Cases

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Introduction Schwannomas at an intramedullary location constitute only 0.3% of primary spinal tumors. Those in the conus are extremely rare, especially in the absence of neurofibromatosis, with only 12 cases reported in the literature so far, excluding the present case. Case presentation We report the case of a 27-year-old female who presented with complaints of backache since 1 year, weakness in both lower limbs with tingling and numbness since 6 months, and urinary incontinence since 1 month. There was no history of trauma or any skin lesions. Magnetic resonance imaging (MRI) of the spine provided a provisional diagnosis of ependymoma. The patient was operated upon, histopathology revealed it to be a schwannoma. Discussion Intramedullary schwannomas without neurofibromatosis are extremely rare at the conus and can be completely resected unless there is infiltration. Gliomas and ependymomas are commoner entities at this site, which are usually subtotally resected. This case highlights that although extremely rare, the possibility of a schwannoma may be considered in the differentials of an intramedullary spinal lesion.

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“…Therefore, unless a predominantly extramedullary component or nerve root thickening is observed, a definitive pre-operative diagnosis of intramedullary schwannoma is difficult to determine based solely on MRI data ( 4 , 5 ). However, only 50% of intramedullary schwannomas are directly connected with nerve roots ( 17 ). Hence, performing GTR without sacrificing the nerve roots is feasible in the majority of intramedullary schwannoma cases.…”

Section: Discussionmentioning

confidence: 99%

Coexisting intramedullary schwannoma with an ependymal cyst of the conus medullaris: A case report

Yang

et al. 2014

Oncology Letters

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Synchronous spinal intramedullary ependymal cysts and intramedullary schwannomas are rare. To the best of our knowledge, the present study is the first report of a case of intramedullary schwannoma coexisting with an ependymal cyst. A 35-year-old male presented with lower back pain and weakness in the left leg. Magnetic resonance imaging identified an intramedullary cystic-solid lesion at the thoracolumbar junction of T11-L2; based on the clinical presentation and radiological features, a pre-operative diagnosis of ependymoma was formed. Subsequently, the patient underwent a T11-12 laminectomy via a posterior approach, with intraoperative monitoring of somatosensory and motor-evoked potentials, achieving a gross total resection of the tumor with a well-demarcated dissection plane. Post-operative histopathological examination demonstrated a schwannoma coexisting with the ependymal cyst, and the neurological status of the patient markedly improved compared with the pre-operatively observed neurological deficit.

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Schwannoma of the conus medullaris: a rare case

Cited by 6 publications

References 12 publications

Schwannoma with an uncommon anal location

Schwannoma with an uncommon anal location

Intramedullary schwannoma of conus medullaris: rare site for a common tumor with review of literature

Coexisting intramedullary schwannoma with an ependymal cyst of the conus medullaris: A case report

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