1999
DOI: 10.1002/(sici)1521-4141(199911)29:11<3691::aid-immu3691>3.0.co;2-l
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Schistosoma mansoni schistosomula reduce E-selectin and VCAM-1 expression in TNF-α-stimulated lung microvascular endothelial cells by interfering with the NF-κB pathway

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Cited by 38 publications
(26 citation statements)
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“…Recently, we have shown that schistosomula increased the concentration of intracellular cAMP and promoted the phosphorylation of the CREB transcription factor in EC [7,8]. In the present study, we provide evidence that the cAMP/PKA signaling pathway is responsible for IL-6 synthesis in HLMVEC.…”
Section: Discussionsupporting
confidence: 73%
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“…Recently, we have shown that schistosomula increased the concentration of intracellular cAMP and promoted the phosphorylation of the CREB transcription factor in EC [7,8]. In the present study, we provide evidence that the cAMP/PKA signaling pathway is responsible for IL-6 synthesis in HLMVEC.…”
Section: Discussionsupporting
confidence: 73%
“…Since we have recently shown that SESP contain bioactive lipophilic compounds [8,10], we tested the effects of the organic phase of the SESP on IL-6 secretion. As shown in Fig.…”
Section: Pge 2 Is the Major Schistosomula-derived Factor Involved Inmentioning
confidence: 99%
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