Scalp Necrosis Revealing Severe Giant-Cell Arteritis

Idoudi, Safa; Kahla, Marouene Ben; Mselmi, Fares; Sriha, Badreddine; Guiga, A.; Ayachi, S.; Belajouza, C.; Denguezli, M.

doi:10.1155/2020/8130404

Cited by 7 publications

(4 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In addition, 29% of patients with GCA reportedly had maxillary artery involvement on positron emission tomography ( 7 ). Although there are scattered reports of skin ulceration of the scalp in GCA ( 8 - 10 ), extensive skin ulceration along the course of the facial artery, as in our case, has not been reported. Skin ulcers may be seen in cases of coexisting atherosclerotic lesions or arterial thrombi, but in the present case, the atherosclerotic findings were mild, and no obvious arterial thrombi were observed.…”

Section: Discussioncontrasting

confidence: 55%

Giant Cell Arteritis That Presented with Buccal Skin Ulceration along the Facial Artery

et al. 2023

View full text Add to dashboard Cite

A 68-year-old man presented with right buccal ulceration along the facial artery, temporal pain, lagophthalmos, diplopia, and tongue deviation to the right. Contrast-enhanced computed tomography showed bilateral temporal artery and right maxillary artery wall thickening, and a diagnosis of giant cell arteritis (GCA) was made according to the American College of Rheumatology 1990 criteria. Treatment with corticosteroids ameliorated his symptoms. This is the first report of GCA with buccal skin ulceration along a facial artery. Because a delayed diagnosis can lead to irreversible damage, it is essential to notice rare symptoms, such as skin ulceration and multiple cranial neuropathy-like symptoms.

show abstract

Section: Discussioncontrasting

confidence: 55%

Giant Cell Arteritis That Presented with Buccal Skin Ulceration along the Facial Artery

et al. 2023

View full text Add to dashboard Cite

show abstract

“…However, when necrosis is established, surgery is often required to remove all necrotic tissue and minimize the risk of severe bacterial infections. 24 , 28 , 29 Skin-graft may be needed to improve wound closure. Noteworthy, no single case of scalp necrosis recurrence has been reported after the onset of appropriate treatment.…”

Section: Ischemic Mucocutaneous Manifestations Of Giant Cell Arteritimentioning

confidence: 99%

A Review of the Dermatological Complications of Giant Cell Arteritis

Prieto-Peña¹,

Castañeda²,

Atienza‐Mateo³

et al. 2021

CCID

View full text Add to dashboard Cite

Giant cell arteritis (GCA) is characterized by granulomatous inflammation of large and medium-sized vessels. It is the most common vasculitis among elderly people in Europe and North America. GCA usually presents with ischemic cranial manifestations such as headache, scalp tenderness, visual manifestations, and claudication of the tongue and jaw. Thickness and tenderness of temporal arteries are the most recognizable signs of GCA on physical examination. Laboratory tests usually show raised acute phase reactants. Skin manifestations are uncommon in GCA and are rarely found as a presenting symptom of GCA. Necrosis of the scalp and tongue is the most common ischemic cutaneous manifestation of GCA. Although infrequent, when present it reflects severe affection and poor prognosis of GCA. Panniculitis-like lesions have been reported in the setting of GCA, with nodules being the most common finding. Other entities, such as generalized granuloma annulare or basal cell carcinoma have been occasionally described in GCA patients. Prompt recognition and initiation of therapy are crucial to prevent serious complications of GCA. When high suspicion of GCA exists, immediate administration of glucocorticoids is recommended. It is advisable to refer the patient to a specialist GCA team for further multidisciplinary assessment.

show abstract

“…Atypical presentations of GCA can also present with undifferentiated constitutional symptoms (pyrexia of unknown origin (PUO), fatigue, weight loss) and organ-related ischaemia or inflammatory disorders including mucocutaneous (lingual and scalp necrosis, panniculitis),7–12 neurological (mononeuritis multiplex, cerebral vasculitis, cranial nerve palsies, acute stroke),13–17 ocular (uveitis, choroidal infarction),18–21 musculoskeletal (peripheral joint arthritis, focal myositis)22–24 and inflammatory pseudotumour (skin, uterine, breast),25–28 along with orchitis, myocardial infarction and mesenteric ischaemia 29–32…”

Section: Discussionmentioning

confidence: 99%

Atypical giant cell arteritis presentations diagnosed with FDG-18 whole body PET imaging

Vijayaraghavan¹,

Martin

Jayawickrama³

et al. 2023

BMJ Case Rep

View full text Add to dashboard Cite

Two male patients aged above 70 years were investigated for chronic non-specific symptoms and evidence of significant systemic inflammation, but without classic ‘cranial symptoms’ of giant cell arteritis (GCA). Each patient had multiple non-diagnostic investigations, but finally extensive large-vessel vasculitis was revealed by whole body positron emission tomography/CT imaging. Both cases were confirmed to have GCA on temporal artery biopsy and responded well to initial high-dose prednisolone therapy. The patients successfully completed 12 months of steroid-sparing therapy with tocilizumab and achieved remission of their condition.

show abstract

Scalp Necrosis Revealing Severe Giant-Cell Arteritis

Cited by 7 publications

References 8 publications

Giant Cell Arteritis That Presented with Buccal Skin Ulceration along the Facial Artery

Giant Cell Arteritis That Presented with Buccal Skin Ulceration along the Facial Artery

A Review of the Dermatological Complications of Giant Cell Arteritis

Atypical giant cell arteritis presentations diagnosed with FDG-18 whole body PET imaging

Contact Info

Product

Resources

About