Scaffolds containing chitosan/carboxymethyl cellulose/mesoporous wollastonite for bone tissue engineering

Sainitya, R.; Sriram, M.; Kalyanaraman, Vani; Thangaraj, Parimelazhagan; Sekaran, Saravanan; Vairamani, M.; Sastry, T. P.; Selvamurugan, N.

doi:10.1016/j.ijbiomac.2015.07.016

Cited by 119 publications

(61 citation statements)

References 34 publications

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“…These cells were incubated in medium (25 mg/ mL) conditioned with scaffolds (CS/CaPP, CS/CaPP/0.25%Pg) as described previously. 24 Cells without treatment served as control. After incubation, cells were harvested and subjected to cell count and viability assays by using MUSE™ Cell Analyzer (Merck-Millipore, Germany) according to the manufacturer's protocol.…”

Section: Cell Viability Cell Count and Cell Cycle Phase Analysesmentioning

confidence: 99%

Proliferation and differentiation of mesenchymal stem cells on scaffolds containing chitosan, calcium polyphosphate and pigeonite for bone tissue engineering

et al. 2017

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Objectives: Treatment of critical-sized bone defects with cells and biomaterials offers an efficient alternative to traditional bone grafts. Chitosan (CS) is a natural biopolymer that acts as a scaffold in bone tissue engineering (BTE). Polyphosphate (PolyP), recently identified as an inorganic polymer, acts as a potential bone morphogenetic material, whereas pigeonite (Pg) is a novel iron-containing ceramic. In this study, we prepared and characterized scaffolds containing CS, calcium polyphosphate (CaPP) and Pg particles for bone formation in vitro and in vivo.

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Section: Cell Viability Cell Count and Cell Cycle Phase Analysesmentioning

confidence: 99%

Proliferation and differentiation of mesenchymal stem cells on scaffolds containing chitosan, calcium polyphosphate and pigeonite for bone tissue engineering

et al. 2017

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“…Carboxymethyl cellulose (CMC) is a naturally occurring polysaccharide soluble in water with no harmful dissolution by‐products . It is an anionic polyelectrolyte and has been demonstrated with the ability to form PECHs with CTS . In the present study, we prepared a novel PECH of CTS and CMC by SD‐A‐SGT method.…”

Section: Introductionmentioning

confidence: 99%

Preparation of chitosan and carboxymethylcellulose‐based polyelectrolyte complex hydrogel via SD‐A‐SGT method and its adsorption of anionic and cationic dye

Zhao

Xing

Qin

et al. 2020

J of Applied Polymer Sci

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The excellent properties of the polyelectrolyte complex hydrogels (PECHs) prepared with polysaccharides only, including polyampholyte, low toxicity, green, and clean production, have endowed them great application potentials as the adsorbents for dye‐containing wastewater treatments. In the current study, the PECH of chitosan (CTS) and carboxymethylcellulose (CMC) was prepared by semi‐dissolution acidification sol–gel transition (SD‐A‐SGT) method. The hydrogel was formed by the strong electrostatic interaction of cationic NH3+ groups of CTS and the anionic COO− groups of CMC. This simple but efficient means exhibited great potentials in constructing PECHs with uniform composition and controllable sol–gel transitions. Molecular dynamics simulation was first employed to predict the formation process and the microstructure of PECHs prepared by SD‐A‐SGT method. The structure and properties of the CTS‐CMC PECHs were also characterized by Fourier transform infrared spectroscopy, SS 13C‐NMR, scanning electron microscopy, mechanical tests, and rheological measurements, respectively. Taking the advantage of amphoteric polyelectrolyte properties, adsorption properties of anionic and cationic dyes were investigated using sunset yellow FCF and methylene blue as model dyes, respectively. The PECHs prepared in the present work had good adsorption capacity for both cationic and anionic dyes with maximum adsorption capacity of 212.83 mg/g for sunset yellow FCF and 167.35 mg/g for methylene blue. Therefore, this PECH would be a promising environmentally friendly adsorbent for the treatment of functional molecules with different charges.

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“…It was reported that wollastonite and pseudowollastonite show a high bioactivity in the simulated body environment [43]. Thus, this kind of ceramic is considered as an excellent material for formation scaffolds and other composite materials which offers advancements in bone repair [24,44]. However, in our previous paper, we showed that wollastonite particles can be successfully incorporated into the porous oxide layer during the anodizing process [18,19].…”

Section: Raman Spectroscopymentioning

confidence: 92%

“…The best electrochemical parameters for the titanium alloy surfaces' treatment in the suspensions were determined in our previous works [18,19]. Wollastonite is a biocompatible compound that enhances osseointegration [24]. The wollastonite particles were …”

Section: Microstructure Of the Modified Titanium Alloy Surfacesmentioning

confidence: 99%

Influence of Alkali Treatment on Anodized Titanium Alloys in Wollastonite Suspension

Kazek-Kęsik

Leśniak

Korotin

et al. 2017

Metals

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Abstract:The surface modification of titanium alloys is an effective method to improve their biocompatibility and tailor the material to the desired profile of implant functionality. In this work, technologically-advanced titanium alloys-Ti-15Mo, Ti-13Nb-13Zr and Ti-6Al-7Nb-were anodized in suspensions, followed by treatment in alkali solutions, with wollastonite deposition from the powder phase suspended in solution. The anodized samples were immersed in NaOH or KOH solution with various concentrations with a different set of temperatures and exposure times. Based on their morphologies (observed by scanning electron microscope), the selected samples were investigated by Raman and X-ray photoelectron spectroscopy (XPS). Titaniate compounds were formed on the previously anodized titanium surfaces. The surface wettability significantly decreased, mainly on the modified Ti-15Mo alloy surface. Titanium alloy compounds had an influence on the results of the titanium alloys' surface modification, which caused the surfaces to exhibit differential physical properties. In this paper, we present the influence of the anodization procedure on alkali treatment effects and the properties of obtained hybrid coatings.

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Scaffolds containing chitosan/carboxymethyl cellulose/mesoporous wollastonite for bone tissue engineering

Cited by 119 publications

References 34 publications

Proliferation and differentiation of mesenchymal stem cells on scaffolds containing chitosan, calcium polyphosphate and pigeonite for bone tissue engineering

Proliferation and differentiation of mesenchymal stem cells on scaffolds containing chitosan, calcium polyphosphate and pigeonite for bone tissue engineering

Preparation of chitosan and carboxymethylcellulose‐based polyelectrolyte complex hydrogel via SD‐A‐SGT method and its adsorption of anionic and cationic dye

Influence of Alkali Treatment on Anodized Titanium Alloys in Wollastonite Suspension

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