2011
DOI: 10.1007/s13596-011-0043-1
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Saussurea lappa (Kuth root): review of its traditional uses, phytochemistry and pharmacology

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Cited by 57 publications
(32 citation statements)
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“…The smoke of roots powder which is used as a substitute for opium when inhaled makes the patient to fall asleep fast. [618] In the present study, both cholinesterases inhibitory activity was reported with an IC 50 value of 58.68 ± 0.86 μg/mL for AchE and 94.46 ± 0.5 μg/mL for BuchE inhibition. Petroleum ether roots extract of S. lappa at doses of 100, 300 mg/kg i.p increased the seizure threshold by means of GABAnergic mechanistic pathway.…”
Section: Discussionsupporting
confidence: 52%
“…The smoke of roots powder which is used as a substitute for opium when inhaled makes the patient to fall asleep fast. [618] In the present study, both cholinesterases inhibitory activity was reported with an IC 50 value of 58.68 ± 0.86 μg/mL for AchE and 94.46 ± 0.5 μg/mL for BuchE inhibition. Petroleum ether roots extract of S. lappa at doses of 100, 300 mg/kg i.p increased the seizure threshold by means of GABAnergic mechanistic pathway.…”
Section: Discussionsupporting
confidence: 52%
“…Saussurea lappa is another herb widely distributed in high altitude areas of India including Kashmir, Lahaul Spiti, and Uttarakhand w [107]. The plant possesses various medicinal values such as antiulcer, anticonvulsant, anticancer, hepatoprotective, antiarthritic, antiviral, and antigout [108].…”
Section: Compositaementioning
confidence: 99%
“…Lipschitz (Asteraceae), commonly known as costus or kuth, is a valuable medicinal herb from North West Himalaya. The species is well known for its extensive use in several indigenous systems of medicine, such as Ayurveda, Unani, Sidha, Tibetan and Chinese, as anodyne, antiarthritic, antiseptic, aphrodisiac, carminative, expectorant and vermifuge (Chevallier, 1996;Chauhan, 1999;Madhuri et al, 2012). Diverse pharmacological studies have convincingly established its anti-inflammatory (Gokhale et al, 2002), anticancer (Ko et al, 2005), hepatoprotective (Chen et al, 1995), antiulcer (Mitra et al, 1996), hypoglycemic (Chaturvedi et al, 1995) and antimicrobial (Yu et al, 2007) effects, providing the required support to the rationale behind its traditional uses.…”
Section: Introductionmentioning
confidence: 99%