SAT-302-Predicting the severity of hepatic steatosis and fibrosis by transient elastography and MRI-based techniques in adults patients with suspected NAFLD

Harrison, Stephen A.; Roberts, K.; Lisanti, Christopher J.; Schwope, Ryan B.; Cebe, Katherine; Aden, James K; Paradis, Valérie; Bédossa, Pierre; Whitehead, Jennifer; Paredes, Angelo H.

doi:10.1016/s0618-8278(19)31534-8

Cited by 1 publication

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Conversely, cT1 is superior to MRE in stratification of NASH as shown in NAFLD cohorts in the UK, US and Japan, as preliminary data show [140,141]. In NAFLD cohorts cT1 strongly correlated with NAFLD activity score [102] and ballooning [32], with an AUROC of 0.84 for diagnosis so it may have utility in earlier detection and diagnosis of disease activity.…”

Section: Not Applicablementioning

confidence: 99%

Multiparametric MR mapping in clinical decision-making for diffuse liver disease

Thomaides-Brears¹,

Lepe

Banerjee³

et al. 2020

Abdom Radiol

View full text Add to dashboard Cite

Accurate diagnosis, monitoring and treatment decisions in patients with chronic liver disease currently rely on biopsy as the diagnostic gold standard, and this has constrained early detection and management of diseases that are both varied and can be concurrent. Recent developments in multiparametric magnetic resonance imaging (mpMRI) suggest real potential to bridge the diagnostic gap between non-specific blood-based biomarkers and invasive and variable histological diagnosis. This has implications for the clinical care and treatment pathway in a number of chronic liver diseases, such as haemochromatosis, steatohepatitis and autoimmune or viral hepatitis. Here we review the relevant MRI techniques in clinical use and their limitations and describe recent potential applications in various liver diseases. We exemplify case studies that highlight how these techniques can improve clinical practice. These techniques could allow clinicians to increase their arsenals available to utilise on patients and direct appropriate treatments.

show abstract

Section: Not Applicablementioning

confidence: 99%