SARS-CoV-2 and the reproductive system: assessment of risk and recommendations for infection control in reproductive departments

Li, Guanjian; Li, Weiran; Bin, Song; Wu, Huan; Tang, Dongdong; Wang, Chao; He, Xiaojin; Cao, Yunxia

doi:10.1080/19396368.2020.1817627

Cited by 5 publications

(1 citation statement)

References 19 publications

(19 reference statements)

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“…SARS-CoV-2 infection can cause systemic local inflammation, and due to the imperfect blood testis/vas deferens/epididymis barrier, SARS-CoV-2 may propagate to the male reproductive tract [164]. However, the virus cannot replicate in the male reproductive system, it may persist, and this phenomenon may be due to the special immunity of testis [165,166]. These results suggest that sexual transmission may be an important link in the prevention of transmission.…”

Section: Malementioning

confidence: 96%

COVID-19: systemic pathology and its implications for therapy

Shen¹,

Li²,

Zhang³

et al. 2022

Int. J. Biol. Sci.

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Responding to the coronavirus disease 2019 (COVID-19) pandemic has been an unexpected and unprecedented global challenge for humanity in this century. During this crisis, specialists from the laboratories and frontline clinical personnel have made great efforts to prevent and treat COVID-19 by revealing the molecular biological characteristics and epidemic characteristics of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Currently, SARS-CoV-2 has severe consequences for public health, including human respiratory system, immune system, blood circulation system, nervous system, motor system, urinary system, reproductive system and digestive system. In the review, we summarize the physiological and pathological damage of SARS-CoV-2 to these systems and its molecular mechanisms followed by clinical manifestation. Concurrently, the prevention and treatment strategies of COVID-19 will be discussed in preclinical and clinical studies. With constantly unfolding and expanding scientific understanding about COVID-19, the updated information can help applied researchers understand the disease to build potential antiviral drugs or vaccines, and formulate creative therapeutic ideas for combating COVID-19 at speed.

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Section: Malementioning

confidence: 96%

COVID-19: systemic pathology and its implications for therapy

Shen¹,

Li²,

Zhang³

et al. 2022

Int. J. Biol. Sci.

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Effect of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) on reproductive system

Wang

Qin

et al. 2021

Stem Cell Research

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Since the emergence of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection in December 2019, it has rapidly spread across many countries and it has become a crucial global health concern. Furthermore, SARS-CoV-2 infection not only effect on respiratory system, but on reproductive system of human. However, there has been not any review described the transmission paths and effects of SARS-CoV-2 infection on human reproductive system, systematically. In order to describe the transmission paths of SARS-CoV-2, effect on the male/female reproductive system of SARS-CoV-2 and some successful prevention measures. We would like to review effect of SARS-CoV-2 on reproductive system. To conclude, SARS-CoV-2 infection might damage to male reproductive system via ACE2 receptor mediating and male patients were reportedly slightly more affected than women by SARS-CoV-2 infections .

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