SARS-CoV-2: a potential novel etiology of fulminant myocarditis

Chen, Chen; Zhou, Yiwu; Wang, Dao Wen

doi:10.1007/s00059-020-04909-z

Cited by 354 publications

(374 citation statements)

References 26 publications

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“…Two of the indicators significantly increased in ICU patients were NT-proBNP and troponin I. It is reported that the infection of 2019-nCoV may cause fulminant myocarditis (12,13). The abnormalities of NT-proBNP and troponin I in ICU patients may suggest that there was a higher preponderance of heart injury in patients who were admitted to the ICU.…”

Section: Resultsmentioning

confidence: 98%

Clinical Characteristics of 28 Patients with Diabetes and COVID-19 in Wuhan, China

et al. 2020

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Objective: Previous studies on coronavirus disease 2019 (COVID-19) were based on information from the general population. We aimed to further clarify the clinical characteristics of diabetes with COVID-19. Methods: Twenty-eight patients with diabetes and COVID-19 were enrolled from January 29, 2020, to February 10, 2020, with a final follow-up on February 22, 2020. Epidemiologic, demographic, clinical, laboratory, treatment, and outcome data were analyzed. Results: The average age of the 28 patients was 68.6 ± 9.0 years. Most (75%) patients were male. Only 39.3% of the patients had a clear exposure of COVID-19. Fever (92.9%), dry cough (82.1%), and fatigue (64.3%) were the most common symptoms, followed by dyspnea (57.1%), anorexia (57.1%), diarrhea (42.9%), expectoration (25.0%), and nausea (21.4%). Fourteen patients were admitted to the intensive care unit (ICU). The hemoglobin A1c level was similar between ICU and non-ICU patients. ICU patients had a higher respiratory rate, higher levels of random blood glucose, aspartate transaminase, bilirubin, creatine, N-terminal prohormone of brain natriuretic peptide, troponin I, D-dimers, procalcitonin, C-reactive protein, ferritin, interleukin (IL)-2R, IL-6, and IL-8 than non-ICU patients. Eleven of 14 ICU patients received noninvasive ventilation and 7 patients received invasive mechanical ventilation. Twelve patients died in the ICU group and no patients died in the non-ICU group. Conclusion: ICU cases showed higher rates of organ failure and mortality than non-ICU cases. The poor outcomes of patients with diabetes and COVID-19 indicated that more supervision is required in these patients. Abbreviations: COVID-19 = coronavirus disease 2019; ICU = intensive care unit; MERS-CoV = middle East respiratory syndrome-related coronavirus; 2019- nCoV = 2019 novel coronavirus; NT-proBNP = N-terminal prohormone of brain natriuretic peptide; SARS-CoV = severe acute respiratory syndrome-related coronavirus

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Section: Resultsmentioning

confidence: 98%

Clinical Characteristics of 28 Patients with Diabetes and COVID-19 in Wuhan, China

et al. 2020

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“…It is associated with other suggestive signs such as septal lines, pleural effusion, large pulmonary veins and mediastinal lymphadenopathy. It has been reported that COVID-19 might be responsible for acute myocarditis [20]. This diagnosis should be suspected if there are signs of interstitial pulmonary edema such as septal lines in younger patients (Fig.…”

Section: Non-infectious Causes Of Acute Ggomentioning

confidence: 98%

COVID-19 pneumonia: A review of typical CT findings and differential diagnosis

Hani

Trieu

Saab

et al. 2020

Diagnostic and Interventional Imaging

383

334

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a b s t r a c tThe standard of reference for confirming COVID-19 relies on microbiological tests such as real-time polymerase chain reaction (RT-PCR) or sequencing. However, these tests might not be available in an emergency setting. Computed tomography (CT) can be used as an important complement for the diagnosis of COVID-19 pneumonia in the current epidemic context. In this review, we present the typical CT features of COVID-19 pneumonia and discuss the main differential diagnosis.

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“…While the predominant presenting symptoms of COVID-19 are respiratory, a case report described a patient in Italy with chest pain and electrocardiographic changes for which the cardiac catheterization lab was activated. Notably, the patient was found to be free of obstructive coronary artery disease but ultimately tested positive for COVID-19 (50 (44,52).…”

Section: Myocardial Injury Myocarditis and Acute Coronary Syndromesmentioning

confidence: 99%

Cardiovascular Considerations for Patients, Health Care Workers, and Health Systems During the COVID-19 Pandemic

Driggin

Madhavan

Bikdeli

et al. 2020

Journal of the American College of Cardiology

1,883

1,931

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SARS-CoV-2: a potential novel etiology of fulminant myocarditis

Cited by 354 publications

References 26 publications

Clinical Characteristics of 28 Patients with Diabetes and COVID-19 in Wuhan, China

Clinical Characteristics of 28 Patients with Diabetes and COVID-19 in Wuhan, China

COVID-19 pneumonia: A review of typical CT findings and differential diagnosis

Cardiovascular Considerations for Patients, Health Care Workers, and Health Systems During the COVID-19 Pandemic

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