Sarcopenia negatively affects hip structure analysis variables in a group of Lebanese postmenopausal women

Abstract

Background: The current study's purpose is to compare hip structural analysis variables in a group of postmenopausal women with sarcopenia and another group of postmenopausal women with normal skeletal muscle mass index. To do so, the current study included 8 postmenopausal women (whose ages ranged between 65 and 84 years) with sarcopenia and 60 age-matched controls (with normal skeletal muscle mass index (SMI)). Body composition and bone parameters were evaluated by dual-energy X-ray absorptiometry (DXA). Results: Weight, lean mass, body mass index, femoral neck cross-sectional area (FN CSA), FN section modulus (Z), FN cross sectional moment of inertia (CSMI), intertrochanteric (IT) CSA, IT Z, IT CSMI, IT cortical thickness (CT), femoral shaft (FS) CSA, FS Z and FS CSMI were significantly greater (p < 0.05) in women with normal SMI compared to women with sarcopenia. In the whole population, SMI was positively associated with IT CSA, IT Z, IT CSMI, IT CT, FS CSA, FS Z, FS CSMI, FS CT but negatively correlated to IT buckling ratio (BR) and FS BR. Conclusion: The current study suggests that sarcopenia has a negative effect on hip bone strength indices in postmenopausal women.

Triglyceride Glucose–Body Mass Index Is a Reliable Indicator of Bone Mineral Density and Risk of Osteoporotic Fracture in Middle-Aged and Elderly Nondiabetic Chinese Individuals

“…In this study, we also investigated the association between TyG-BMI and femoral neck geometry. A recent study showed that several conditions associated with altered bone metabolism (for example, sarcopenia) result in poor femoral neck geometry, suggesting that these indices on DXA scans may be a good indicator of bone health [ 39 ]. Consistent with a previous Chinese study [ 40 ], we found that CSA, CT, SM, CSMI, and CSI decrease with age, whereas BR increases with age.…”

Main findings and advances in bioinformatics and biomedical engineering- IWBBIO 2018

“…Following, the paper presented by Hayman Saddik et al [12] suggests that sarcopenia negatively affects hip bone strength indices in postmenopausal women. As a conclusion, the authors state that implementing strategies to increase skeletal muscle mass index (SMI) in postmenopausal women may be useful for preventing osteoporotic fractures.…”