Sarcoidosis and bronchial carcinoma: Description of a case

Sarcoidosis

“…lt is probably because the occasional concurrence of a common cancer with sarcoidosis is not unexpected that few reports of the concurrence of lung cancer and sarcoidosis have been published, mainly to draw attention to diagnostic difficulties (jefferson et Goodbody and Taylor, 1957;Ellman and Hanson, 1958;]örgensen, 1963a;Sakula, 1963;Sarkar, 534 Sarcoidosis 1970; Schoenfield et al, 1978). The following two ca ses illustrate the diagnostic problems that may arise.…”

Noncaseating pulmonary granulomas associated with small cell carcinoma of the lung

“…Granulomatous reactions in association with bronchogenic carcinoma have been described in mediastinal [2, 23,24], supraclavicular [25], scalene [24], and hilar [ 23,241 lymph nodes, and can sometimes obscure the diagnosis of malignancy. Granulomatous reactions within regional nodes were demonstrated in 11 of 325 patients (3.4 percent) with bronchogenic carcinoma described by Jepsen [26] and in 20 of 630 patients (3.2 percent) with bronchogenic carcinoma described by Laurberg [27].…”

“…Ellman and Harson [28] reported noncaseating granulomas in lung, spleen, liver, and scalene lymph nodes in a patient with bronchogenic carcinoma of the right lower lobe. Goodbody and Taylor [25] found noncaseating granulomas on supraclavicular lymph node biopsy, but two years later demonstrated squamous cell carcinoma of the lung and noncaseating granulomas within the resected lung tissue and hilar nodes. Schoenfeld et al 1291 also reported noncaseating granulomas in resected lung from a patient with squamous cell carcinoma.…”