Sarcoidosis after Adjustable Silicone Gastric Banding – a Report of Two Cases in Germany

Böttger, J.; Meyer, Frank; Lippert, H.; Mussack, Thomas

doi:10.1159/000235865

Cited by 8 publications

(5 citation statements)

References 10 publications

(7 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It is widely recognized that sarcoidosis tends to appear more frequently in scars, tattoos, and foreign bodies 26 . The literature also describes sarcoidosis after silicone gastric banding 27 and filler injection for cosmetic purposes, 28 which might be related to ASIA.…”

Section: Discussionmentioning

confidence: 99%

Sarcoidosis Presenting as Late Seroma Mimicking Breast Implant–Associated Anaplastic Large Cell Lymphoma

Ibarra

Vallejo²,

Rivera³

et al. 2021

Ann Plast Surg

View full text Add to dashboard Cite

Late seroma related to breast silicone implants is a rare complication. Interest for its characterization has grown after its association with the recently described breast implant–associated anaplastic large cell lymphoma. The differential diagnosis includes infectious diseases, mechanical and traumatic causes, tumors, postpartum seroma, and inflammatory, allergic, or idiopathic causes. Sarcoidosis has been associated with breast silicone implants over the last decades, but it has never been reported as a cause of breast effusion. We describe a rare presentation of sarcoidosis as a late breast implant seroma simulating the clinical features and radiologic findings of breast implant–associated anaplastic large cell lymphoma and highlight that sarcoidosis can be suspected by the presence of nonnecrotizing epithelioid granulomas in the cytology, with a characteristic inverted ratio of CD4/CD8 T cells. The aims of this article are to review the current evidence about sarcoidosis related to silicone implants and breast cancer, provide a new alternative in the differential diagnosis of late seroma, and advise the scientific community how early implant removal can improve the disease.

show abstract

Section: Discussionmentioning

confidence: 99%

Sarcoidosis Presenting as Late Seroma Mimicking Breast Implant–Associated Anaplastic Large Cell Lymphoma

Ibarra

Vallejo²,

Rivera³

et al. 2021

Ann Plast Surg

View full text Add to dashboard Cite

show abstract

“…The role of silicone as a trigger in the development of sarcoidosis may be considered with both local (sarcoid granulomas in the skin at the site of silicone mammoplasty or subcutaneous injection) and, most importantly, systemic manifestations of sarcoidosis with the formation of granulomas in the lung tissue and hilar lymph nodes [24][25][26]. Cases of the development of pulmonary sarcoidosis with the involvement of the intracranial lymph nodes during the implantation of an intragastric silicone balloon are also described; the appearance of radiographic changes in the lung tissue was noted as early as 7 days after surgery [27].…”

Section: Major Criteriamentioning

confidence: 99%

Sarcoidosis and Autoimmune Inflammatory Syndrome Induced by Adjuvants

Старшинова

Zinchenko

Малкова

et al. 2023

Life

View full text Add to dashboard Cite

Currently, sarcoidosis remains one of the diseases with unknown etiology, which significantly complicates its diagnosis and treatment. Various causes of sarcoidosis have been studied for many years. Both organic and inorganic trigger factors, provoking the development of granulomatous inflammation are considered. However, the most promising and evidence-based hypothesis is the development of sarcoidosis as an autoimmune disease, provoked by various adjuvants in genetic predisposed individuals. This concept fits into the structure of the autoimmune/inflammatory syndrome, induced by adjuvants (ASIA) that was proposed in 2011 by Professor Shoenfeld Y. In this paper, the authors reveal the presence of major and minor ASIA criteria for sarcoidosis, propose a new concept of the course of sarcoidosis within the framework of ASIA, and point out the difficulties in creating a model of the disease and the selection of therapy. It is obvious that the data obtained not only bring us closer to understanding the nature of sarcoidosis, but also potentiate new studies confirming this hypothesis by obtaining a model of the disease.

show abstract

“…Silicone granulomas have been reported in association with renal failure and hypercalcemia . Pulmonary sarcoidosis has been reported 7 days after adjustable silicone gastric banding . Sarcoidal granulomas after augmentation mammoplasty with silicone went into remission after the removal of silicone gel implants …”

Section: Silicone Granulomas and Sarcoidosis: Two Sides Of The Same Cmentioning

confidence: 99%

“…19 Pulmonary sarcoidosis has been reported 7 days after adjustable silicone gastric banding. 20 Sarcoidal granulomas after augmentation mammoplasty with silicone went into remission after the removal of silicone gel implants. 21 I have observed two patients (unpublished data), who developed cutaneous or pulmonary sarcoidosis after small amounts of pure liquid silicone in the lips.…”

Section: Blocking T-cell Activationmentioning

confidence: 99%

Commentary: Tacrolimus in the Treatment of Chronic and Refractory Late-Onset Immune-Mediated Adverse Effects Related to Silicone Injections

Duffy¹

2012

Dermatologic Surgery

View full text Add to dashboard Cite

Sarcoidosis after Adjustable Silicone Gastric Banding – a Report of Two Cases in Germany

Cited by 8 publications

References 10 publications

Sarcoidosis Presenting as Late Seroma Mimicking Breast Implant–Associated Anaplastic Large Cell Lymphoma

Sarcoidosis Presenting as Late Seroma Mimicking Breast Implant–Associated Anaplastic Large Cell Lymphoma

Sarcoidosis and Autoimmune Inflammatory Syndrome Induced by Adjuvants

Commentary: Tacrolimus in the Treatment of Chronic and Refractory Late-Onset Immune-Mediated Adverse Effects Related to Silicone Injections

Contact Info

Product

Resources

About