Sarcoidosis

Stanbury, Rosalyn M; Graham, Elizabeth; Murray, Philip I.

doi:10.1097/00004397-199503530-00010

Cited by 10 publications

(3 citation statements)

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“…Sarcoidosis is a multisystem disorder, consisting of granulomatous inflammation of unknown etiology with a histological hallmark of noncaseating granulomas composed of epithelioid cells and Langerhans giant cells [5]. Posterior segment findings in ocular sarcoidosis have been shown to occur in 14-28% of [6,7].…”

Section: Discussionmentioning

confidence: 99%

Choroidal granuloma as an initial manifestation of systemic sarcoidosis

Verma

Biswas

2009

Int Ophthalmol

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Systemic sarcoidosis presenting as a choroidal nodule is a rare phenomenon, with limited reports in the past. We present a case of systemic sarcoidosis in a young adult male presenting as a solitary choroidal mass. The diagnosis was made based on elevated serum lysozyme, serum angiotensin-converting enzyme, negative Mantoux, and computed tomography (CT) scan of the chest. Ultrasound examination and fundus fluorescein angiography helped us to differentiate this lesion from choroidal melanoma. Magnetic resonance imaging (MRI) of brain was done to rule out neurosarcoidosis. Patient responded well to systemic steroid therapy, with marked resolution of the choroidal granuloma, and reduced size of mediastinal lymph nodes on repeat CT scan of the chest.

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Section: Discussionmentioning

confidence: 99%

Choroidal granuloma as an initial manifestation of systemic sarcoidosis

Verma

Biswas

2009

Int Ophthalmol

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“…S a rcoidosis, generally affecting young and middleaged adults, is an inflammatory disease of unknown etiology whose histologic hallmark is the presence of noncaseating granulomas composed of epithelioid cells and Langerhans giant cells. Any organ system may be affected, but more frequent involvement may be seen in the lungs, liver, skin, central nervous system, and eyes (3).…”

Section: Discussionmentioning

confidence: 99%

Conjunctival Deposits as the First Sign of Systemic Sarcoidosis in a Pediatric Patient

Çaça

Ünlü

Büyükbayram

et al. 2006

European Journal of Ophthalmology

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“…In Brazil, a prevalence below 10/100,000 persons is estimated (2) . Papers show that the disease is more commonly seen among young adults in their third to fourth decade of life (3,4) . Eye involvement happens in 25 to 50% of patients presenting systemic sarcoidosis (5) .…”

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confidence: 99%