Sarcoid of Boeck in the Negro

Irgang, S.

doi:10.1001/archderm.1947.01520110105012

Cited by 6 publications

(6 citation statements)

References 2 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…11 Clinically, these may manifest as maculopapules, nodules, plaques, subcutaneous nodules, infiltrative scars, and lupus pernio. [1][2][3][4][5][6][7][8][9] Review of a report of 54 black South Africans with cutaneous manifestations of sarcoidosis and systemic disease revealed one verrucous appearing lesion. 22 Verrucous cutaneous sarcoidosis was first described by Irgang in 1950, and subsequently, only rare cases have been reported in the literature (Table 1).…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Verrucous Cutaneous Sarcoidosis

Stockman

Rosenberg²,

Bengana

et al. 2013

The American Journal of Dermatopathology

View full text Add to dashboard Cite

Sarcoidosis is a multisystem disorder of unknown origin, characterized by the accumulation of lymphocytes and mononuclear histiocytes inducing the formation of noncaseating "naked" epithelioid granulomas. The lungs, lymphatic system, and skin are most often affected, but sarcoidosis may affect any organ. Cutaneous involvement of sarcoidosis is often the sentinel sign of the disease, with the skin sometimes being exclusively affected. We present a case of a 54-year-old African American woman with long-standing history of pulmonary sarcoidosis that presented with multiple verrucous cutaneous lesions on the upper and lower extremities mimicking carcinoma. The initial cutaneous biopsy was superficial in nature, and the pathologist raised the consideration of a possible keratoacanthoma. A deeper skin shave biopsy was performed, and the histopathology showed verrucous pseudoepitheliomatous epidermal hyperplasia with scattered noncaseating granulomas in the superficial dermis. Stains (acid-fast bacillus, Periodic acid-Schiff, and Gomori-Grocott methenamine silver stains) were negative for microorganisms. Given the clinical setting and histomorphology of the cutaneous lesions, the diagnosis of verrucous sarcoidosis was rendered. Verrucous sarcoidosis is a rare cutaneous manifestation of sarcoidosis that could be easily misdiagnosed if it is not appropriately biopsied. This hinders the precise evaluation of the histological specimen, overall clinical picture, and administration of appropriate therapy.

show abstract

Section: Discussionmentioning

confidence: 99%

“…[1][2][3][4][5][6][7][8][9] Because cutaneous sarcoidosis can exhibit many different morphologies, cutaneous sarcoidosis is known as one of the "great imitators" in dermatology. Infiltration with noncaseating granulomas is the hallmark of the disease, and it may result in various clinical manifestations.…”

Section: Introductionmentioning

confidence: 99%

Verrucous Cutaneous Sarcoidosis

Stockman

Rosenberg²,

Bengana

et al. 2013

The American Journal of Dermatopathology

View full text Add to dashboard Cite

show abstract

“…Cutaneous sarcoidosis can be divided into specific (papules and plaques) and nonspecific lesions (erythema nodosum). Verrucous sarcoidosis is a specific cutaneous type that has been cited in the literature on five occasions 1 –5 . All of the cases occurred in black patients aged 21–27 years with only one female case described 2 .…”

mentioning

confidence: 99%

“…Verrucous sarcoidosis is a specific cutaneous type that has been cited in the literature on five occasions 1 –5 . All of the cases occurred in black patients aged 21–27 years with only one female case described 2 . The presentation varied between verruccous lesions occurring alone 5 or in association with ulcerative, 2 , 4 papillomatous 1 or the more typical papular lesions 3 .…”

mentioning

confidence: 99%

“…All of the cases occurred in black patients aged 21–27 years with only one female case described 2 . The presentation varied between verruccous lesions occurring alone 5 or in association with ulcerative, 2 , 4 papillomatous 1 or the more typical papular lesions 3 . The lesions principally involved the lower limbs with one case showing a generalized distribution 3 .…”

mentioning

confidence: 99%

See 1 more Smart Citation