Sampling, occurrence and evaluation of PCDDs and PCDFs from incinerated solid urban waste

Cavallaro, A.; Bandi, G.; Invernizzi, G.; Luciani, L; Mongini, E.; Gorni, A.

doi:10.1016/0045-6535(80)90038-7

Cited by 46 publications

(10 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…TCDD is formed by incineration of waste materials and in the procedures involved in herbicide production, paper processing and plastics manufacturing, in particular the production polyvinyl chloride. 1,2) Thus, humans are involuntarily exposed to TCDD through the diet and gradually accumulate it throughout their lifetime. Exposure to TCDD can result in a variety of adverse responses including carcinogenesis, reproductive toxicity, immune dysfunction, hepatotoxicity, tetatogenicity, and endocrine changes.…”

Section: Introductionmentioning

confidence: 99%

Curcumin Anticipates the Suppressed Body Weight Gain with 2,3,7,8-Tetrachlorodibenzo-p-Dioxin in Mice

Ishida

Taketoh

Nakatsune

et al. 2004

JOURNAL OF HEALTH SCIENCE

View full text Add to dashboard Cite

The protective effect of curcumin, a potent inducer of heat shock protein (Hsp) 70, against the acute toxicity produced by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) was studied in vivo in C57BL/6J mice. Curcumin reduced the loss of body weight gain produced by TCDD regardless of having no effect on hepatomegaly and thymic atrophy. Hsp70.1 mRNA levels in liver and intestine were unaffected or tended to be reduced by TCDD and/or curcumin treatment. Curcumin also had no effect on the induction of hepatic ethoxyresorufin O-deethylase activity by TCDD. These data suggest that curcumin exhibits a protective effect against some forms of dioxin toxicity by a mechanism(s) distinct from the increase in hepatic and intestinal Hsp70 and inhibition of arylhydrocarbon receptor activation.

show abstract

Section: Introductionmentioning

confidence: 99%

Curcumin Anticipates the Suppressed Body Weight Gain with 2,3,7,8-Tetrachlorodibenzo-p-Dioxin in Mice

Ishida

Taketoh

Nakatsune

et al. 2004

JOURNAL OF HEALTH SCIENCE

View full text Add to dashboard Cite

show abstract

“…These are further defined below: 164 Bumb et aI., 171 Cavallaro et aI., 172 and Lustenhouwer et al 173 Over the past 10 years, numerous studies have continued to investigate this issue and PCDD/PCDFs have been the focus of many national and international symposia and conferencesY4…”

Section: ----------mentioning

confidence: 99%

Incineration of Hazardous Waste: A Critical Review Update

1993

View full text Add to dashboard Cite

“…This focus originated with the initial belief that certain chlorophenols and their derivatives were the major sources of TCDD contamination in the environment. More recent studies by our laboratory (3)(4)(5) and by a few other groups (6)(7)(8)(9)(10) have shown that various combustion processes, for example, municipal refuse incinerators, can be significant sources of a broad spectrum of PCDDs and PCDFs, as well as other related chlorinated organic compounds (chlorophenols, cholorobenzenes) which may be involved in formation of the former. Other events which have called increasing attention to the PCDFs in the U.S. recently are the occurrences of fires and breakdowns in PCB-filled electrical devices (transformers and capacitors), with resultant environmental contamination and, in some cases, human exposures to toxic PCDFs produced in these combustion processes.…”

Section: Introductionmentioning

confidence: 99%

Sources and Fate of Polychlorinated Dibenzodioxins, Dibenzofurans and Related Compounds in Human Environments

Tiernan¹,

Taylor²,

Garrett³

et al. 1985

Environmental Health Perspectives

View full text Add to dashboard Cite

Several of the major incidents resulting in potential human exposures to polychlorinated dibenzodioxins (PCDDs) and/or polychlorinated dibenzofurans (PCDFs), polychlorinated biphenyls (PCBs) and related compounds which have occurred in the U.S. in recent periods have resulted from improper disposal of hazardous chemical wastes. Prominent examples of such environmental contamination episodes are the Love Canal, into which ton quantities of chlorinated organic compounds containing substantial concentrations of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) were deposited; numerous sites in the State of Missouri which were contaminated by the dumping of chlorinated organic wastes containing various PCDDs and possibly PCDFs, and PCBs; and the environs of a 2,4-D/2,4,5-T manufacturing plant site in Arkansas, which were contaminated with PCDDs. Environmental assessments of such sites have revealed extensive contamination of soils, waterways, fish and other biological species with these toxic compounds, which in turn could lead to human exposures. Other recently identified sources of PCDDs, PCDFs and related compounds in human environments include stack effluents from municipal refuse incineration, and fires and explosions involving electrical devices containing PCBs and polychlorinated benzenes. Data obtained in assessments of such incidents are presented, and the implications of these findings with respect to the distribution and persistence of PCDDs, PCDFs and related chemicals in the environment and possible effects on humans are discussed.

show abstract

Sampling, occurrence and evaluation of PCDDs and PCDFs from incinerated solid urban waste

Cited by 46 publications

References 6 publications

Curcumin Anticipates the Suppressed Body Weight Gain with 2,3,7,8-Tetrachlorodibenzo-p-Dioxin in Mice

Curcumin Anticipates the Suppressed Body Weight Gain with 2,3,7,8-Tetrachlorodibenzo-p-Dioxin in Mice

Incineration of Hazardous Waste: A Critical Review Update

Sources and Fate of Polychlorinated Dibenzodioxins, Dibenzofurans and Related Compounds in Human Environments

Contact Info

Product

Resources

About