2020
DOI: 10.1371/journal.pone.0240007
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Sampling manholes to home in on SARS-CoV-2 infections

Abstract: About 50% of individuals infected with the novel Coronavirus (SARS-CoV-2) suffer from intestinal infection as well as respiratory infection. They shed virus in their stool. Municipal sewage systems carry the virus and its genetic remnants. These viral traces can be detected in the sewage entering a wastewater treatment plant (WTP). Such virus signals indicate community infections but not locations of the infection within the community. In this paper, we frame and formulate the problem in a way that leads to al… Show more

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Cited by 33 publications
(49 citation statements)
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“…Our recent paper in PLOS ONE , “Sampling manholes to home in on SARS-CoV-2 infections” [ 5 ], provides additional background and motivation, as well as building blocks that we use here. We have written this new paper to be self-contained, and we extend earlier results in important ways.…”
Section: Framing the Problem And Reviewing The Literaturementioning
confidence: 99%
See 4 more Smart Citations
“…Our recent paper in PLOS ONE , “Sampling manholes to home in on SARS-CoV-2 infections” [ 5 ], provides additional background and motivation, as well as building blocks that we use here. We have written this new paper to be self-contained, and we extend earlier results in important ways.…”
Section: Framing the Problem And Reviewing The Literaturementioning
confidence: 99%
“…We describe our generalized “Tributary Search Algorithm” that seeks to find the source manhole. In contrast to our earlier paper [ 5 ], the generalization is required due to the more complex and realistic sewer network tree structure at street intersections, as described earlier. Here we are applying Algorithm 1, seeking a single infected person (Newbie) in an otherwise uninfected community.…”
Section: The Generalized Tributary Search Algorithmmentioning
confidence: 99%
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