Salivary tumours?experience over thirty years

Abstract

A clinicopathological survey of tumours of salivary glands seen in a special surgical clinic at the Christie Hospital and Holt Radium Institute is reported. Nine hundred and seventy-seven benign and malignant tumours have been seen within the past 30 years. The results of treatment are included with particular attention to those of the parotid glands which present the greatest therapeutic problem. The approach to surgical treatment of pleomorphic adenomas is described in detail and guidelines offered as to the procedure that should be used based on full exploration and assessment of each tumour. The need for adjuvant irradiation depends on the standard of surgery that is done. The relationship between carcinomas and benign adenomas is discussed and the need for surgery in all cases is stressed in order to make a definite histological diagnosis in view of the wide range of pathological abnormality encountered.

Neutron radiotherapy for recurrent pleomorphic adenomas of major salivary glands

“…Patients in whom a complete surgical extirpation of their disease is not possible, 12 patients in whom sacrifice of the facial nerve is necessary for complete tumor removal, or patients in whom multiple recurrences have occurred seem to benefit from radiotherapy. 6,12,13 Ample evidence is available to suggest that fast neutron radiotherapy is more efficacious for salivary gland tumors of both major and minor salivary gland tumors than conventional radiotherapy, particularly in the setting of gross residual disease.…”

Extracapsular dissection for clinically benign parotid lumps: reduced morbidity without oncological compromise

“…Between 1952 and 1992, 821 patients with previously untreated epithelial parotid neoplasia were treated at the Christie Hospital, Manchester (Renehan et al, , 1999Gleave et al, 1979). The preoperative diagnosis was made on clinical grounds; fine needle aspiration cytology was not used.…”

Extra-capsular dissection for benign parotid tumours

“…This procedure was initially described by GLEAVE 4 and involves careful dissection of the benign parotid tumour in a plane 3-4 mm peripheral to the tumour capsule without identification of the facial nerve. ECD differs from enucleation, because the tumour is removed with an intact capsule as opposed to shelling out the tumour contents and leaving the capsule in situ as is the case with enucleation 12 .…”