Salivary tumours

Abstract

The classification and management of salivary gland tumours can be problematic for a variety of reasons. These tumours are not common, and additionally show a very wide range of cell types and morphological configurations between various tumour types, and sometimes even within a single tumour mass. Microscopic interpretation of excision specimens can also be confounded by artefactual changes resulting from the increasing use of pre-operative fine-needle aspiration biopsies. Moreover, the behaviour of many of the tumours is unpredictable. For example, pleomorphic adenoma, the most common salivary gland neoplasm, whilst a benign tumour, has a propensity to recur and also to progress to malignancy. On the other hand, tumours such as acinic cell carcinoma and mucoepidermoid carcinoma, although frankly malignant, can sometimes behave in a relatively lowgrade manner. In the parotid gland, the presence of the facial nerve can cause significant difficulties in both pre-operative diagnosis and surgical excision.For all these reasons, close liaison between the surgical team, histopathologists, radiologists and oncologists is particularly critical to ensure optimal management of patients with these tumours.

FNA biopsy of secondary nonlymphomatous malignancies in salivary glands: A multi‐institutional study of 184 cases

“…SMSGs, in contrast to primary salivary gland tumors, occur more commonly in men . The male‐to‐female ratio in our study was 2.4:1, compared with ratios of 1.7:1 and 2.1:1 in 2 earlier studies .…”

“…SMSGs, in contrast to primary salivary gland tumors, occur more commonly in men. 58,59 The male-to-female ratio in our study was 2.4:1, compared with ratios of 1.7:1 and 2.1:1 in 2 earlier studies. 1,3 The greatest difference in sex was observed among patients who had malignant melanoma, with a male-to-female ratio 5.1:1 in our study cohort.…”

An endonasal approach to the resection of a papillary seromucinous adenocarcinoma of the Eustacian tube

“…A surgical approach is more appropriate for low-grade, low-stage adenocarcinomas. While the 5-year disease survival of patients with adenocarcinoma of the nasopharynx is approximately 65%, non-randomized studies demonstrate a survival benefit with the involvement of a surgical approach [10]. …”

Patterns of salivary tumours at a university teaching hospital in Kenya

“…Due to the relatively few numbers of large scale epidemiological studies and in addition, to the considerable variation in the inclusion criteria makes comparison difficult [12]. In our study SGTs consisted 5.4% of all the orofacial lesions whose biopsies were examined.…”