Salivary immunoglobulin levels in juvenile autoimmune hepatitis

Damasceno, Juliana Ximenes; Guedes, Maria Izabel Florindo; Leite, Christiane Araujo Chaves; Monteiro, André Jalles; Fonteles, M. C.; Jimenez, Maria Esther Zurita; Lima, Vilma; Ribeiro, Thyciana Rodrigues; Fonteles, Cristiane Sá Roriz

doi:10.1016/j.archoralbio.2018.04.014

Cited by 3 publications

(3 citation statements)

References 33 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…6 Teeth about to exfoliate, with pathological mobility, in eruption or with purulent exudate according to Romero et al 21 were not included. The gingival health was assessed by a single calibrated examiner with an intra-examiner Kappa of 0.81 26 for both indices. The calibration was performed with 18 healthy children.…”

Section: Data Collectionmentioning

confidence: 99%

See 1 more Smart Citation

Salivary immunoglobulin levels and periodontal indices in Brazilian children with and without type 1 diabetes

RIBEIRO,

SILVA,

MARTINS

et al. 2024

Braz. oral res.

Self Cite

View full text Add to dashboard Cite

This cross-sectional study evaluated the association between salivary immunoglobulins, plaque index, and gingival index in Brazilian children with and without type 1 diabetes mellitus (DM1). The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) checklist for the reporting of observational studies was followed. The DM1 group had 38 children, and an equal number of volunteers matched by sex and age were recruited as controls. Clinical examination was performed for plaque index and gingival index determination. Non-stimulated whole saliva was collected. Concentrations of IgA, IgG, and IgM were determined by ELISA test. Data were tested by the Kolmogorov-Smirnov, Mann-Whitney, and Spearman tests and a multiple linear regression model (p<0.05) was performed. Gingival index was higher in the Control (DM1: 0.16±0.17; Control: 0.24±0.23, p=0.040). In DM1, there was a correlation between IgA and age (rho=0.371, p=0.024), IgM and IgG (rho=0.459, p=0.007), and IgM and gingival index (rho=0.394, p=0.014). In DM1, multiple linear regression showed that age (p=0.041; β=0.363), gingival index (p=0.041; β=0.398), and plaque index (p=0.008; β=-0.506) were good predictors of IgA levels in saliva. Thus, IgA was the only researched immunoglobulin that was directly associated with plaque and gingival indices in Brazilian children with DM1, but not in control subjects.

show abstract

Section: Data Collectionmentioning

confidence: 99%

“…This standardized protocol was used to control for environmental and circadian rhythm influences on the qualitative and quantitative salivary components. 26…”

Section: Data Collectionmentioning

confidence: 99%

Salivary immunoglobulin levels and periodontal indices in Brazilian children with and without type 1 diabetes

RIBEIRO,

SILVA,

MARTINS

et al. 2024

Braz. oral res.

Self Cite

View full text Add to dashboard Cite

show abstract

“…The racional behind the technique used in this study is that some antibody associated with allergy found in the bloodstream can also be found in the saliva, thus allowing them to be identified through immunologycal testing [10,11]. In view of the above stated, this study aimed to verify the possibility of using saliva to detect IgG 1 for the diagnosis of food allergy.…”

Section: Introductionmentioning

confidence: 99%

Detection of serum and salivary IgE and IgG1 immunoglobulins specific for diagnosis of food allergy

et al. 2019

Self Cite

View full text Add to dashboard Cite

Given the growing incidence and prevalence of life-threatening food allergies, health concerns have raised new perspectives for in vivo and in vitro diagnostic methodologies, pointing to saliva as a promising material, already used to diagnose other pathologies. Based on the above considerations, this study aimed to verify the possible use of saliva for the detection of IgE and IgG 1 in the diagnosis of food allergy. This was a randomized, cross-sectional clinical study with a quantitative approach, developed at a hospital referral center in allergy in the state of Ceará, from January to July 2015. The sample consisted of 36 children of both sexes, aged between 1 and 60 months, with a diagnosis of cow's milk protein allergy (CMPA) by the RAST test. Children hospitalized or under immunosuppressive drugs were excluded from the study. Serum and saliva samples of the participants were collected and subsequently subjected to the indirect immunoenzymatic assay (ELISA) for the detection of specific serum and salivary immunoglobulins for food: corn, papaya, cow's milk, egg white, wheat, soybeans, peanuts, nuts, kiwi, cacao, fish, shrimp, bananas and tomatoes. For comparison of serum and saliva results, the T-test of independent samples and Mann-Whitney were adopted, for samples with normal and non-normal distribution respectively. A confidence interval of 95% was adopted for significant results. It was observed that 100% (n = 36) of the participants presented cow's milk allergy through the indirect ELISA, detecting IgE or IgG 1 in serum and saliva. When serum IgE and IgG 1 concentrations were compared, there was no statistical difference (p > 0.05) in 12 of the 14 foods evaluated. The same amount (n = 12) of non-significant differences (p > 0.05) was observed in the comparison of the 14 foods under IgE and IgG 1 contractions in saliva. In the verification of the average values of IgE present in the serum and saliva of the foods, only cow's milk, fish and papaya showed statistically significant differences (p < 0.05). Of the total food evaluated, only the average levels of IgG 1 present in serum and saliva showed a significant value (p < 0.05) in banana and tomato. These findings indicate that the detection of IgE and IgG 1 in saliva proves to be as efficient as in the serum. The use of the salivary technique for use in the diagnosis of food allergy is suggested.

show abstract

Salivary immunoglobulins (A, G, and M) in type 1 diabetes mellitus patients: A PROSPERO-registered systematic review and meta-analysis

Martins

Costa

Silva

et al. 2021

Archives of Oral Biology

View full text Add to dashboard Cite

Salivary immunoglobulin levels in juvenile autoimmune hepatitis

Cited by 3 publications

References 33 publications

Salivary immunoglobulin levels and periodontal indices in Brazilian children with and without type 1 diabetes

Salivary immunoglobulin levels and periodontal indices in Brazilian children with and without type 1 diabetes

Detection of serum and salivary IgE and IgG1 immunoglobulins specific for diagnosis of food allergy

Salivary immunoglobulins (A, G, and M) in type 1 diabetes mellitus patients: A PROSPERO-registered systematic review and meta-analysis

Contact Info

Product

Resources

About