Saline dressing versus povidone iodine dressing in chronic diabetic foot ulcer healing: a prospective comparative study

Kulkarni, Srinivas; Venkatesh, S; Kruthi, S R

doi:10.18203/2349-2902.isj20191551

Cited by 2 publications

(2 citation statements)

References 7 publications

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“…Wang et al 21 found no significant evidence to suggest that silver dressings promote wound healing and limited infection in chronic wounds any more than other types of wound dressings. Other evidence focusing on topical antimicrobials involving polyherbal formulations have demonstrated the positive impact on wound healing rates in healing diabetic wounds after repeated application and follow-up 22 . Mandrika et al 23 also found that the anti-inflammatory plant extracts consisting of 13 herbal ingredients with copper sulfate fortified in oil were most active against clinical strains of multidrug resistant bacteria, and suggested the evidence provides support for the use of various herbs in the use of polyherbal formulations for non-healing wounds.…”

Section: Topical Antimicrobialsmentioning

confidence: 99%

What is the evidence that there is antimicrobial resistance associated with the use of topical antimicrobial preparations?

Blackburn¹,

Ousey²,

Patton³

et al. 2023

WPR

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Aims This review aimed to examine the effect of using topical antimicrobial preparations on antimicrobial resistance (AMR) by critically evaluating the currently available evidence.Method Using systematic review methodology, we considered original research studies employing a prospective design and written in English. The search was conducted in July 2022 using Ovid MEDLINE, Ovid EMBASE Medline and CINAHL databases. Data were extracted using a pre-designed extraction tool and all included studies were quality appraised using the Evidence Based Literature (EBL) appraisal checklist.Results A total of 375 studies were identified, with 25 meeting the inclusion criteria. Studies were conducted between 1998 and 2021. Half of the studies included explored the use of silver in dressings as an antimicrobial. Two studies were performed in a hospital setting, one study employed an in vitro and in vivo design, with all remaining studies employing an in vitro approach. ConclusionThere was limited evidence of the effect of topical antimicrobial preparations on AMR, with most included studies exploring the effectiveness of topical antimicrobials on infection and wound healing. AMR remains an important issue for exploration and understanding to clearly determine whether topical antimicrobials contribute to AMR.

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Section: Topical Antimicrobialsmentioning

confidence: 99%

What is the evidence that there is antimicrobial resistance associated with the use of topical antimicrobial preparations?

Blackburn¹,

Ousey²,

Patton³

et al. 2023

WPR

View full text Add to dashboard Cite

show abstract

“…Chronic diabetic wounds, in our setup are treated with debridement if necessary, regular wound dressing following a thorough wash with hydrogen peroxide, povidone iodine, normal saline and empirical antibiotics after culture and sensitivity testing 5 .…”

Section: Introductionmentioning

confidence: 99%

Comparative Analysis of Topical Insulin Dressing Vs Normal Saline Dressing in Diabetic Foot Ulcers Wound Healing

Ghayour,

Irem,

ullah

et al. 2024

PJMHS

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Background: Foot ulcers, a dangerous and common consequence of diabetes, currently have no particular therapeutic options. There are many topical medicines and ointments available for wound management.It has been observed that topical insulin dressings effectiveness is better than other dressings. Aim: To determine the effectiveness of Topical Insulin dressing VS Normal saline dressing in diabetic ulcer in terms of rate of reduction in ulcer area in days and need for re debridement Methods: A randomized control trial conducted in Emergency and Outdoor Department of South Surgical ward, Mayo Hospital, Lahore.Study was carried out insix months from Sept 2022 to March 2023. A total 86 patients fulfilling the selection criteria presented to outdoor/Emergency of South surgical department of general surgery of Mayo Hospital, Lahore falling in Wagner’s classification I and IIwere enrolled in the study after taking informed consent. Patients were divided by method of random allocation (lottery method) to Group A (Topical insulin dressing) and Group B (Normal saline soaked dressing) after explaining the procedure. Rate of reduction in ulcer area was measured in days. Need of re-debridement was labeled as ‘yes’ if patient needed re-debridement or ‘no’ if patient did not need re-debridement. Results: Baseline mean wound area in Group A and in Group B was 34.87±29.23 cm2 and 27.45±24.00cm2. After 2 weeks the wound area reduced to 9.35±10.75 cm2 and 7.33±9.29 cm2 respectively. Mean days for rate of reduction in ulcer areas was significantly less in Group A patients than in Group B patients (p-value<0.001). Rate of re-debridement for Group B patients was significantly higher than patients in Group A (Group A: 18.6% vs Group B: 46.5%, p-value= 0.006). Improved wound healing will reduce need of redebridement and minor to major foot amputations. Conclusion: This study concludes that topical insulin dressing is more effective as that of normal saline soaked dressing for management of diabetic ulcer in terms of rate of reduction in ulcer area in term of days and need for re debridement. Keywords: Effectiveness, Normal saline Dressing, Topical Insulin dressing, Diabetic foot ulcer, Ulcer area, Re-debridement.

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Saline dressing versus povidone iodine dressing in chronic diabetic foot ulcer healing: a prospective comparative study

Cited by 2 publications

References 7 publications

What is the evidence that there is antimicrobial resistance associated with the use of topical antimicrobial preparations?

What is the evidence that there is antimicrobial resistance associated with the use of topical antimicrobial preparations?

Comparative Analysis of Topical Insulin Dressing Vs Normal Saline Dressing in Diabetic Foot Ulcers Wound Healing

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