Safety of rehabilitation interventions for patients with hematologic diseases associated with low blood counts—verification focusing on blood cancer

Abstract

This study aimed to establish unique criteria for hematologic patients with low blood counts in the borderline region of or below the threshold for discontinuing cancer rehabilitation without meeting the criteria for blood transfusion, and to investigate the physical symptoms and activities of daily living. [Participants and Methods] Among the 251 participants, 128 had blood test results below the discontinuation criteria. They were permitted to engage in rehabilitation interventions by a hematologist based on the new criteria. The remaining 123 patients were classified under the discontinuation group. The Barthel Index scores during admission and discharge were compared between the two groups, in terms of chemotherapy, physical symptoms of nausea, petechial hemorrhage, pyrexia, and diarrhea. [Results] There was no significant difference between the two groups in terms of the Barthel Index score during admission or discharge. Pyrexia occurred more frequently in patients managed under the new criteria. [Conclusion] Patients with low blood counts that fall between the criteria for discontinuing rehabilitation and receiving blood transfusions can continue undergoing rehabilitation interventions with the permission of their doctors, provided that measures are taken to manage adverse events. This strategy prevents activities of daily living reduction.

Rehabilitation intervention safety in patients with malignant lymphoma with low blood cell counts

“…In a previous study 1) and in this study, we examined continuous rehabilitation intervention after consultation with a hematologist. As a result, the patient's motor function was maintained without any adverse events associated with exercise intervention, suggesting the possibility of continuous rehabilitation intervention for hematology patients with low blood cell counts.…”

“…We investigated physical symptoms and ADL in a group of patients who were allowed to undergo rehabilitation intervention. Compared to the rehabilitation discontinuation group, the new criteria group reported a shorter hospitalization period, no decline in ADL function, and no adverse events associated with exercise intervention 1) .…”

Frequency of Extended Red Cell Antigen Phenotype Among Patients of Hematological Diseases: A Single Center Study

“…Despite advances in the management of hematologic diseases, these patients often reach a stage where regular blood transfusions are required to maintain their health [2]. Blood transfusion is one of the critical interventions in patients with hematological diseases presenting with symptomatic anemia [3], which requires a compatible and safe transfusion of blood or its components [4]. However, the alloimmunization of red blood cells (RBC) is a major adverse effect of blood transfusion [5].…”