Safety, feasibility, and effectiveness of a novel spray cryotherapy technique in a canine model

Duan, Hongxia; Xuan, Li; Long, Xuan; Liu, Xinyang; Xie, Shuanshuan; Wang, Changhui

doi:10.1002/ctm2.315

Cited by 6 publications

(10 citation statements)

References 3 publications

(3 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Local cooling can be helpful in the treatment of swelling, alleviation of pain, or local vasoconstriction. The highest effectiveness of this treatment is achieved within the first 72 h post-trauma [ 21 ]. Selected injured body areas are locally cooled in this way most often, but short-term cooling of the entire body in a cryo chamber is applied in physiotherapy as well [ 22 ].…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Selected Techniques for Physiotherapy in Dogs

Dybczyńska

Goleman

Garbiec

et al. 2022

Animals

View full text Add to dashboard Cite

Physiotherapy is a new dynamically developing field of science in which the original idea was to improve the care for convalescent patients. Its positive effects observed in humans suggested the need for the adaptation and implementation of human physiotherapy techniques in animal care. Dogs are the second group of animals that undergo physiotherapy most frequently. These animals are diagnosed with a number of locomotor system problems, which may be congenital and are often related to the breed or acquired. The aim of the study was to collect and systematize knowledge of animal physiotherapy with emphasis on the selection and description of the most important aspects of canine physiotherapy. The review material consisted of 59 publications, with 230 selected for the review. Physiotherapeutic treatments are applied not only for rehabilitation of animals but also in healthy animals to upgrade their sports performance and improve their welfare. A majority of physiotherapeutic approaches have been transferred from human protocols. A key issue in the achievement of therapy success is the proper selection of physiotherapeutic procedures and close cooperation between the veterinarian and the physiotherapist.

show abstract

Section: Resultsmentioning

confidence: 99%

“…Age-related degeneration-in 35.60% (21) of publications; − Physiotherapy in healthy animals-in 23.73% (14) of publications.…”

mentioning

confidence: 99%

Selected Techniques for Physiotherapy in Dogs

Dybczyńska

Goleman

Garbiec

et al. 2022

Animals

View full text Add to dashboard Cite

show abstract

“…No congestion, edema, stenosis, or scarring were observed throughout the trial, with no instrument or surgery-related complications, and no deaths occurred. 30 Dirk-Jan Slebos recruited and treated 16 subjects at three sites in Europe and Canada, 40 and published literature in 2017 on the e cacy of SCT in chronic bronchitis. However, they did not start a further discussion and analysis on the speci c mechanisms of SCT for chronic bronchitis.…”

Section: Discussionmentioning

confidence: 99%

“…29 Based on the pro le of our previous research, the safety and feasibility of SCT in a canine model of chronic bronchitis has been strongly demonstrated. 30 In this study, we focused on whether this technique provides signi cant improvements in respiratory function and airway tissue morphology, and how long it can be maintained in a large mammalian model of chronic bronchitis. In addition, we further explored the relevant biological mechanisms involved in the improvement of lung function.…”

Section: Introductionmentioning

confidence: 99%

Effect of spray cryotherapy on respiratory function in canine models of chronic bronchitis

Liang

Duan

et al. 2022

Preprint

Self Cite

View full text Add to dashboard Cite

Objective: Our aim was to explore whether SCT is effective in improving respiratory function in a canine model of chronic bronchitis and to further elucidate the associated biological mechanisms. Methods: A total of ten experimental dogs were recruited for this study, eight of which were exposed to sulfur dioxide (SO2) for 6 months as a model group and the other two as healthy controls. We analyzed and compared the differences of respiratory function, airway morphology and inflammatory cell infiltration at 1-, 3- and 6-month intervals after SCT treatment and further explored the intrinsic correlations. Results: Respiratory function was significantly reduced after six months of SO2 exposure compared to healthy controls. PIF and PEF significantly decreased by 30.64% and 18.35%, respectively. Other respiratory function indicators such as TV, tI, tE, MV, EIP, EF25%, EF50%, EF75%, IF25%, IF50%, IF75%, FIaV, FEaV and CI also showed a significant downward trend (P<0.05). Respiratory function and airway morphometry were significantly improved at 1-, 3-, and 6- month intervals after SCT compared to chronic bronchitis group. The number of infiltrated neutrophils and macrophages per unit area of airway epithelium was negatively correlated with respiratory function, implying that decreased respiratory function was accompanied by more infiltration of neutrophils and macrophages. Conclusions: SCT significantly improved respiratory function, airway morphometry and infiltrated inflammatory cell count in a canine model of chronic bronchitis for at least six months. Our study identifies the relevant biological mechanisms by which infiltrating neutrophil and macrophage counts can have a critical impact on respiratory function.

show abstract

“…Details of the device and procedure have been published in our previous article. 13 Prior to the procedure, we requested general anaesthesia for the subject and informed him/her about the risks associated with the procedure and then selected an appropriately sized endoscope. The effect of cryotherapy on the patient's vital signs was checked intraoperatively, while oxygen saturation, arterial partial pressure of oxygen and blood partial pressure of carbon dioxide indicators were monitored.…”

Section: 3mentioning

confidence: 99%

A prospective study of spray cryotherapy in patients with COPD

Liang

Zhang

Duan

et al. 2023

Clinical and Translational Dis

Self Cite

View full text Add to dashboard Cite

A total of eight patients with chronic obstructive pulmonary disease (COPD) were recruited and evaluated for improvements in lung function, exercise capacity, airway morphology and quality of life before and after undergoing spray cryotherapy (SCT) treatment. CAT, COPD assessment test; HE, haematoxylin and eosin; LCQ, Leicester Cough Questionnaire; PAS, periodic acid Schiff; SGRQ, St. George's Respiratory Questionnaire; 6MWD, 6-min walking distance.

show abstract

Safety, feasibility, and effectiveness of a novel spray cryotherapy technique in a canine model

Cited by 6 publications

References 3 publications

Selected Techniques for Physiotherapy in Dogs

Selected Techniques for Physiotherapy in Dogs

Effect of spray cryotherapy on respiratory function in canine models of chronic bronchitis

A prospective study of spray cryotherapy in patients with COPD

Contact Info

Product

Resources

About