Sacroiliitis in systemic lupus erythematosus

Erdogan, Esra; Gökçen, Neslihan; Badak, Suade Ozlem; Bıçakcı, Yunus Kenan; Arslan, Didem

doi:10.1007/s00393-020-00879-z

Cited by 5 publications

(2 citation statements)

References 25 publications

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“… 9 Recently, a study represented higher titer of CRP as a potential risk factor of sacroiliac involvements in lupus patients. 14 We suggest that other risk factors such as EBV reactivation, presence of different lupus specific antibodies should also be evaluated to predict possibility of sacroiliitis as well as rare first manifestations.…”

Section: Case Discussionmentioning

confidence: 99%

Generalized lymphadenopathy in the presence of acute Epstein–Barr virus infection as the initial manifestation of systemic lupus erythematous: A case report

Jazi,

Faraji,

Aghaei

et al. 2024

Clinical Case Reports

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Key Clinical MessageClinicians should carefully consider generalized lymphadenopathy, particularly post viral infections, as one of the possible systemic lupus erythematous (SLE) first signs regarding unusual joint involvements such as sacroiliitis. Late diagnosis of this autoimmune inflammatory disease, could lead to irreversible morbidity and higher mortality.AbstractLymphadenopathy could represent various etiologies, including infections, malignancies, and rheumatologic diseases. SLE is known as the great mimicker which could be presented with different first manifestations. We report a 42‐year‐old woman in the acute phase of Epstein–Barr infection, admitted with polyarticular peripheral arthritis, sacroiliitis, and generalized lymphadenopathy. She had no similar history or taken unpasteurized dairy. Nodes were soft, mobile, and tender without skin change on top. During the process, she was diagnosed with SLE and discharged with prednisolone 30 mg/day and hydroxychloroquine 400 mg/day. After 2 weeks of follow‐up, all lymphadenopathy and symptoms were diminished. This case underscores the thousand faces innate of SLE. Clinical awareness would lead to an accurate diagnosis and early intervention.

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Section: Case Discussionmentioning

confidence: 99%

Generalized lymphadenopathy in the presence of acute Epstein–Barr virus infection as the initial manifestation of systemic lupus erythematous: A case report

Jazi,

Faraji,

Aghaei

et al. 2024

Clinical Case Reports

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show abstract

“…The estimated incidence of SLE and AS are 4.71-5.5/100,000 [1,2] and 5.4-7.3/100,000 [3,4] person-years, respectively. Though mild sacroiliitis can be seen in patients with lupus [5,6], a diagnosis of both lupus and AS in the same patient is uncommon and has been described only in a handful of case reports in the medical literature [7][8][9][10][11][12][13]. Comorbid SLE and AS provide interesting diagnostic and therapeutic challenges.…”

Section: Introductionmentioning

confidence: 99%

Comorbid Ankylosing Spondylitis and Systemic Lupus Erythematosus: A Therapeutic Challenge

DeBoisblanc,

Nava,

Chauhan

et al. 2024

Cureus

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Ankylosing spondylitis (AS) and systemic lupus erythematosus (SLE) are common rheumatologic ailments that cause multiorgan system disease. The incidence of lupus and AS in the same patient is rare and has seldom been described in the literature. Comorbid lupus and AS provide interesting diagnostic and therapeutic challenges. Here, we present a case of comorbid lupus and AS, discuss the diagnostic challenges in diagnosing these conditions, and put forth possible therapeutic interventions that may benefit similar patients.

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A Narrative Literature Review Comparing the Key Features of Musculoskeletal Involvement in Rheumatoid Arthritis and Systemic Lupus Erythematosus

et al. 2022

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Although the clinical approach to the management of musculoskeletal manifestations in systemic lupus erythematosus (SLE) is often similar to that of rheumatoid arthritis (RA), there are distinct differences in immunopathogenesis, structural and imaging phenotypes and therapeutic evidence. Additionally, there are few published comparisons of these diseases. The objective of this narrative literature review is to compare the immunopathogenesis, structural features, magnetic resonance imaging (MRI) and musculoskeletal ultrasound (MSUS) studies and management of joint manifestations in RA and SLE. We highlight the key similarities and differences between the two diseases. Overall, the literature evaluated indicates that synovitis and radiographical progression are the key features in RA, while inflammation without swelling, tendinitis and tenosynovitis are more prominent features in SLE. In addition, the importance of defining patients with RA by the presence or absence of autoantibodies and categorizing patients with SLE by synovitis detected by musculoskeletal ultrasound and by structural phenotype (non-deforming, non-erosive arthritis, Jaccoud’s arthropathy and ‘Rhupus’) with respect to joint manifestations will also be discussed. An increased understanding of the joint manifestations in RA and SLE may inform evidence-based clinical decisions for both diseases.

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Sacroiliitis in systemic lupus erythematosus

Cited by 5 publications

References 25 publications

Generalized lymphadenopathy in the presence of acute Epstein–Barr virus infection as the initial manifestation of systemic lupus erythematous: A case report

Generalized lymphadenopathy in the presence of acute Epstein–Barr virus infection as the initial manifestation of systemic lupus erythematous: A case report

Comorbid Ankylosing Spondylitis and Systemic Lupus Erythematosus: A Therapeutic Challenge

A Narrative Literature Review Comparing the Key Features of Musculoskeletal Involvement in Rheumatoid Arthritis and Systemic Lupus Erythematosus

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