Sabal serrulata extract (Strogen forte) in the treatment of symptomatic benign prostatic hyperplasia

Abstract

The effectivity of Sabal serrulata extract in the treatment of symptomatic prostatic hyperplasia was scrutinized in 38 patients. In the course of the 12-month treatment followed up by examinations, the subjective complaints abated in almost 3/4 of the cases. Adverse effects were not encountered. According to uroflowmetry, the average peak flow rate increased from 10.36 ml/s to 14.44 ml/s (p < 0.0001), while the average middle stream increased from 6.02 ml/s to 7.45 ml/s (p < 0.001). Urinary retention decreased or disappeared in more than 9/10 of the cases. The average amount of the residue decreased by 47 ml (p < 0.001). The average volume of the prostate was reduced by 10.6% (p < 0.02). On the basis of the favourable results, Sabal serrulata extract is recommended in the treatment of prostatic hyperplasia producing symptoms of mild and moderate severity.

A prospective study of the efficacy of Serenoa repens, Tamsulosin, and Serenoa repens plus Tamsulosin treatment for patients with benign prostate hyperplasia

“…This is in contrast with 5-alpha-reductase inhibitors [46]. Prostate volume was found to be decreased by SR in three uncontrolled studies [44,47,48], but this was not confirmed by controlled studies [10,49]. We found a mean decrease in prostate volume of 0.7 cc and 1.0 cc for the SR and TAM groups, respectively, but they were not statistically significant.…”

Effects of pumpkin seed oil and saw palmetto oil in Korean men with symptomatic benign prostatic hyperplasia

“…Kondas et al (1996) reported that the average MFR was increased from 10.36 ml/s to 14.44 ml/s without any adverse effects after 12 months of treatment with saw palmetto oil . In addition, this treatment did not influence the effectiveness of drugs taken for other chronic diseases by these patients.…”

Does the addition of Serenoa repens to tamsulosin improve its therapeutical efficacy in benign prostatic hyperplasia?

“…PV was found to be decreased by SR in 3 uncontrolled stdies [20][21][22] , but this was not confirmed in controlled studies 10,11 .We found the mean decrease in PV of -1.0 mL, -0.7 mL and 0.8 mL for the groups TAM, SR and TAM + SR, respectively, but they were not statistically significant. TAM efficacy does not depend on prostate size and is similar across age group.…”