Sa1373 Comparative Evaluation of Structural and Functional Changes in Pancreas After Endoscopic and Surgical Management of Pancreatic Necrosis

Rana, Surinder Singh; Bhasin, Deepak K.; Chalapathi, Rao; Gupta, Rajesh

doi:10.1016/s0016-5085(13)60978-6

Cited by 9 publications

(13 citation statements)

References 18 publications

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“…[4][5][6][7][8][9] In addition to lower procedure-related morbidity, there is data suggesting that endoscopic necrosectomy leads to preservation of pancreatic parenchyma when compared to surgical necrosectomy, thereby reducing the incidence of diabetes and steatorrhea. 10 Although myriad data exist describing the technical success and short-term outcomes of endoscopic transmural therapy for WON, 6,7,9,11 far less is known regarding longterm outcomes, specifically the effect on health-related quality of life (HR-QOL). The aim of the present study was to examine long-term outcomes and HR-QOL for patients undergoing endoscopic therapy for WON relative to other populations of patients with gastrointestinal disorders.…”

Section: Introduction W Alled -Off Pancreatic Necrosis (Won)mentioning

confidence: 99%

Health‐related quality of life and long‐term outcomes after endoscopic therapy for walled‐off pancreatic necrosis

Smith

Gregory

Elsner

et al. 2018

Digestive Endoscopy

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Section: Introduction W Alled -Off Pancreatic Necrosis (Won)mentioning

confidence: 99%

Health‐related quality of life and long‐term outcomes after endoscopic therapy for walled‐off pancreatic necrosis

Smith

Gregory

Elsner

et al. 2018

Digestive Endoscopy

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“…A study comparing endoscopic drainage and surgical necrosectomy reported by Rana et al [19] found that structural and functional impairment of the pancreas was seen less frequently in patients who had endoscopic drainage than in patients who underwent surgery due to the lower rates of diabetes ( [19,20] In the open abdomen strategy, after necrosectomy and debridement, the abdomen is reopened every 1 to 3 days until all necrosis and/or infected material is removed. In the CPL approach, after necrosectomy and debridement, the abdomen is not reopened, and local lavage, gradually increasing from 4 to 10 liters per 24 hours, is performed continually.…”

Section: Discussionmentioning

confidence: 99%

Risk factors for morbidity in walled-off pancreatic necrosis and performance of the continuous postoperative lavage: a single center experience

Aziret

Ercan²,

Toka³

et al. 2018

Ulus Travma Acil Cerrahi Derg

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BACKGROUND:The aim of this study was to evaluate the risk factors for morbidity in cases of walled-off pancreatic necrosis (WOPN) and the performance of continuous postoperative lavage (CPL) for patients who demonstrated resistance to a minimally invasive approach. METHODS:The study enrolled 19 of 28 consecutive patients with WOPN who underwent surgical treatment or an endoscopic necrosectomy at Sakarya University Education and Research Hospital. The patients were divided into 2 groups according to the length of time from the first diagnosis of acute pancreatitis (AP) (Group 1, n=19) to preoperation or endoscopic necrosectomy (Group 2) (n=19). All of the cases were retrospectively evaluated and compared in terms of demographic features, operative features, and complications. RESULTS:No statistically significant difference was found between the number of complications or the duration of hospital stay in terms of age, body mass index, size of the walled-off pancreatic necrosis, American Society of Anesthesiologists score, Ranson's criteria, operation time, and duration from AP to endoscopic necrosectomy or operation (p>0.05). Performance of an endoscopic necrosectomy was determined to be correlated with a decrease in the number of complications (B=-0.626, 95% confidence interval [CI]: -0.956 to -0.296; p<0.001), and when a high neutrophil-to-lymphocyte ratio (NLR) was detected at first admission, the number of complications was greater (B=0.032, 95% CI: 0.009-0.055; p=0.01). Reproduction in a culture and male gender were found to be risk factors for a prolonged hospital stay (B=0.669, 95% CI: 0.365-0.973; p<0.001), (B=0.484, 95% CI: 0.190-0.778; p=0.003), respectively. CONCLUSION: CPL is a safe and effective surgical treatment approach for WOPN. Reproduction in a culture, male gender, and a high NLR on first admission and a negative or not-available endoscopic necrosectomy were determined to be risk factors for a poor prognosis.

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“…Частота развития экзо-и эндокринной НПЖ после острого панкреатита (ОП), по данным разных авторов, колеблется в пределах 11-85% после тяжелого панкреатита и 13-55% после легкого панкреатита [6,7]. Отмечена тенденция к более тяжелому течению экзокринной и эндокринной НПЖ у больных, перенесших инфицированный панкреонекроз и оперированных по этому поводу, по сравнению с больными, перенесшими стерильный панкреонекроз.…”

Section: глава 1 экзо-и эндокринная недостаточность поджелудочной жеunclassified

Russian consensus on exoand endocrine pancreatic insufficiency after surgical treatment

Khatkov

Маев

Абдулхаков

et al. 2018

Terapevticheskii arkhiv

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The Russian consensus on exo - and endocrine pancreatic insufficiency after surgical treatment was prepared on the initiative of the Russian "Pancreatic Club" on the Delphi method. His goal was to clarify and consolidate the opinions of specialists on the most relevant issues of diagnosis and treatment of exo - and endocrine insufficiency after surgical interventions on the pancreas. An interdisciplinary approach is provided by the participation of leading gastroenterologists and surgeons.

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Sa1373 Comparative Evaluation of Structural and Functional Changes in Pancreas After Endoscopic and Surgical Management of Pancreatic Necrosis

Cited by 9 publications

References 18 publications

Health‐related quality of life and long‐term outcomes after endoscopic therapy for walled‐off pancreatic necrosis

Health‐related quality of life and long‐term outcomes after endoscopic therapy for walled‐off pancreatic necrosis

Risk factors for morbidity in walled-off pancreatic necrosis and performance of the continuous postoperative lavage: a single center experience

Russian consensus on exoand endocrine pancreatic insufficiency after surgical treatment

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