Abstract:The German Society of Anesthesiology and Intensive Care Medicine (DGAI) commissioneda revision of the S2 guidelines on “positioning therapy for prophylaxis or therapy of pulmonary function disorders” from 2008. Because of the increasing clinical and scientificrelevance the guidelines were extended to include the issue of “early mobilization”and the following main topics are therefore included: use of positioning therapy and earlymobilization for prophylaxis and therapy of pulmonary function disorders, undesire… Show more
“…Early mobilization therapy has been mentioned in order to prevent or attenuate physical function impairment in critically ill patients [ 11 ]. However, as studies showed an improved physical function associated to protocol-based early mobilization in a surgical ICU cohort [ 12 ], this could not be proven in patients with acute respiratory failure.…”
Section: Long-term Outcome After Acute Respiratory Distress Syndromementioning
Purpose of reviewTo review the current research data on long-term outcome and health-related quality of life in survivors of the acute respiratory distress syndrome (ARDS) and to compare these findings with those from non-ARDS patients surviving critical illness.Recent findingsBetween 6 months and 2 years after discharge from ICU, survivors of ARDS present with substantial impairments of the levels of body function (muscle strength, walking capacity and/or physical activity (physical SF-36 score). In contrast to non-ARDS patients from surgical ICUs, a standardized intensified physical therapy during early course of illness in ARDS patients could not show an improvement of long-term physical function performance. Furthermore, a substantial part of further ARDS patients suffer from depression (26–33%), anxiety (38–44%) or posttraumatic stress disorder (22–24%). In general, the level of functional autonomy and daily life activities was reduced, and in one study, 6 months after ICU-discharge this level was significantly lower in ARDS patients compared with non-ARDS patients. In a recent study, 44% of ARDS survivors were jobless 1 year after critical illness, whereas half of previously employed patients returned to work within 4 months after hospital discharge. General health-related quality of life was significantly reduced compared with a matched population in all studies.SummarySurviving ARDS is associated with a long-term substantial reduction in health-related quality of life and such a reduction does not differ from findings in patients surviving other critical illness. In further research, a special attention should be paid to prevention measures of the ‘post intensive care syndrome’ as well as to patient important domains, which might better explain the patient's and families’ demands.
“…Early mobilization therapy has been mentioned in order to prevent or attenuate physical function impairment in critically ill patients [ 11 ]. However, as studies showed an improved physical function associated to protocol-based early mobilization in a surgical ICU cohort [ 12 ], this could not be proven in patients with acute respiratory failure.…”
Section: Long-term Outcome After Acute Respiratory Distress Syndromementioning
Purpose of reviewTo review the current research data on long-term outcome and health-related quality of life in survivors of the acute respiratory distress syndrome (ARDS) and to compare these findings with those from non-ARDS patients surviving critical illness.Recent findingsBetween 6 months and 2 years after discharge from ICU, survivors of ARDS present with substantial impairments of the levels of body function (muscle strength, walking capacity and/or physical activity (physical SF-36 score). In contrast to non-ARDS patients from surgical ICUs, a standardized intensified physical therapy during early course of illness in ARDS patients could not show an improvement of long-term physical function performance. Furthermore, a substantial part of further ARDS patients suffer from depression (26–33%), anxiety (38–44%) or posttraumatic stress disorder (22–24%). In general, the level of functional autonomy and daily life activities was reduced, and in one study, 6 months after ICU-discharge this level was significantly lower in ARDS patients compared with non-ARDS patients. In a recent study, 44% of ARDS survivors were jobless 1 year after critical illness, whereas half of previously employed patients returned to work within 4 months after hospital discharge. General health-related quality of life was significantly reduced compared with a matched population in all studies.SummarySurviving ARDS is associated with a long-term substantial reduction in health-related quality of life and such a reduction does not differ from findings in patients surviving other critical illness. In further research, a special attention should be paid to prevention measures of the ‘post intensive care syndrome’ as well as to patient important domains, which might better explain the patient's and families’ demands.
“…In ECMO patients a specific strategy in terms of anticoagulation is mandatory [ 88 ]. Backrest elevated position (20–45°) is the preferred supine position for ARDS patients, since it may contribute to an improvement of oxygenation and respiratory mechanics [ 89 ] compared to “flat” supine, but limitations for backrest elevation (e.g., hemodynamic impairment) must be considered.…”
Purpose: Severe ARDS is often associated with refractory hypoxemia, and early identification and treatment of hypoxemia is mandatory. For the management of severe ARDS ventilator settings, positioning therapy, infection control, and supportive measures are essential to improve survival.
Methods and results:A precise definition of life-threating hypoxemia is not identified. Typical clinical determinations are: arterial partial pressure of oxygen < 60 mmHg and/or arterial oxygenation < 88 % and/or the ratio of PaO 2 /FIO 2 < 100. For mechanical ventilation specific settings are recommended: limitation of tidal volume (6 ml/ kg predicted body weight), adequate high PEEP (>12 cmH 2 O), a recruitment manoeuvre in special situations, and a 'balanced' respiratory rate (20-30/min). Individual bedside methods to guide PEEP/recruitment (e.g., transpulmonary pressure) are not (yet) available. Prone positioning [early (≤ 48 hrs after onset of severe ARDS) and prolonged (repetition of 16-hr-sessions)] improves survival. An advanced infection management/control includes early diagnosis of bacterial, atypical, viral and fungal specimen (blood culture, bronchoalveolar lavage), and of infection sources by CT scan, followed by administration of broad-spectrum anti-infectives. Neuromuscular blockage (Cisatracurium ≤ 48 hrs after onset of ARDS), as well as an adequate sedation strategy (score guided) is an important supportive therapy. A negative fluid balance is associated with improved lung function and the use of hemofiltration might be indicated for specific indications.
Conclusions:A specific standard of care is required for the management of severe ARDS with refractory hypoxemia.
“…This pilot study shows that such a protocol is feasible and safe in minimally-invasive cardiac surgery. Historically, so-called fast-track protocols in cardiac surgery were implemented 20 years ago during the evolution phase of the modern minimally invasive heart surgery [16][17][18]. These early protocols addressed primarily the intraoperative phase and showed the potential for an early extubation on the ICU, shortening of the ICU stay and cost containment in the cardiac surgical setting.…”
Section: Discussionmentioning
confidence: 99%
“…The decision to mobilize the patient is made in consensus with the responsible anaesthetist. During this monitor-guided mobilization, we followed the break-off /stop criteria according to the recommendations of S2 guideline of the German Society of Anaesthesiology and Intensive Care Medicine [17]. First, the physiotherapist checks motoric and sensory functions of upper and lower extremities in supine position as well as the postoperative pain level.…”
Section: Postoperative Early Recovery Protocolmentioning
Protocols for "Enhanced recovery after surgery (ERAS)" are on the rise in different surgical disciplines and represent one of the most important recent advancements in perioperative medical care. In cardiac surgery, only few ERAS protocols have been described in the past.
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