S1259 How Does Bowel Preparation Influence Colonic Motility and Pre-Defecatory Motor Patterns?

Neuroanatomy and physiology of colorectal function and defaecation: from basic science to human clinical studies

“…Bowel preparation has no effect upon the frequency of propulsive motor patterns, their site of origin, or the colonic response to a meal. However, there is a significant increase in the frequency and amplitude of high amplitude propagating sequences (HAPS) (see below) and a significant alteration in the spatiotemporal patterning of propagating motor activity throughout the prepared colon (see below) 35 . These factors should be taken into consideration when comparing colonic data recorded via different techniques.…”

Surgical management of constipation

“…Aside from the considerable leap of faith implicit within this concept, in the absence of proven manometric‐histopathological correlation, are issues of reliability. These have been covered in detail in chapter 3 and in brief include problems of standardization, extent and spacing of recording sites, 62 and use of bowel preparation 63 . Thus such measures should be used with great caution in guiding surgical treatment.…”

“…These have been covered in detail in chapter 3 and in brief include problems of standardization, extent and spacing of recording sites, 62 and use of bowel preparation. 63 Thus such measures should be used with great caution in guiding surgical treatment. Of interest however is the observation that when propagated pressure data for individual patients with STC are displayed as 24-h spatio-temporal maps, it is evident that there is a marked paucity of activity throughout the mid-transverse colon to splenic flexure.…”