Rutin reduces oxidative stress in animals with renovascular hypertension

Duarte, Rayssa; Carvalho, Alynne; Gadelha, Danilo D. A.; Braga, Valdir de Andrade

doi:10.1186/1753-6561-8-s4-p65

Cited by 6 publications

(3 citation statements)

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“…Fagopyum talaricum (tartary buckwheat) (2 n = 8) that belongs to the Polygonaceae family is an important food for health and nutrition so that it has now been introduced in many countries [40]. The rutin in tartary buckwheat can reduce hypertension and arteriosclerosis in addition to exhibiting antioxidant activity, and quercetin shows antimicrobial activity [41–43]. Therefore, tartary buckwheat is also a valuable medicinal plant.…”

Section: Introductionmentioning

confidence: 99%

Genome-wide identification, phylogeny, evolutionary expansion and expression analyses of bZIP transcription factor family in tartary buckwheat

et al. 2019

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Background In reported plants, the bZIP family is one of the largest transcription factor families. bZIP genes play roles in the light signal, seed maturation, flower development, cell elongation, seed accumulation protein, abiotic and biological stress and other biological processes. While, no detailed identification and genome-wide analysis of bZIP family genes in Fagopyum talaricum (tartary buckwheat) has previously been published. The recently reported genome sequence of tartary buckwheat provides theoretical basis for us to study and discuss the characteristics and expression of bZIP genes in tartary buckwheat based on the whole genome. Results In this study, 96 FtbZIP genes named from FtbZIP1 to FtbZIP96 were identified and divided into 11 subfamilies according to their genetic relationship with 70 bZIPs of A. thaliana . FtbZIP genes are not evenly distributed on the chromosomes, and we found tandem and segmental duplication events of FtbZIP genes on 8 tartary buckwheat chromosomes. According to the results of gene and motif composition, FtbZIP located in the same group contained analogous intron/exon organizations and motif composition. By qRT-PCR, we quantified the expression of FtbZIP members in stem, root, leaf, fruit, and flower and during fruit development. Exogenous ABA treatment increased the weight of tartary buckwheat fruit and changed the expressions of FtbZIP genes in group A. Conclusions Through our study, we identified 96 FtbZIP genes in tartary buckwheat and synthetically further analyzed the structure composition, evolution analysis and expression pattern of FtbZIP proteins. The expression pattern indicates that FtbZIP is important in the course of plant growth and development of tartary buckwheat. Through comprehensively analyzing fruit weight and FtbZIP genes expression after ABA treatment and endogenous ABA content of tartary buckwheat fruit, ABA may regulate downstream gene expression by regulating the expression of FtPinG0003523300.01 and FtPinG0003196200.01 , thus indirectly affecting the fruit development of tartary buckwheat. This will help us to further study the function of FtbZIP genes in the tartary buckwheat growth and improve the fruit of tartary buckwheat. Electronic supplementary material The online version of this article (10.1186/s12864-019-5882-z) contains supplementary material, which i...

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Section: Introductionmentioning

confidence: 99%

Genome-wide identification, phylogeny, evolutionary expansion and expression analyses of bZIP transcription factor family in tartary buckwheat

et al. 2019

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“…Multiplebiological activities including the anti-oxidant (Yang, Yang, & Zheng, 2010), hypolipidemic effect (Liu et al, 2009), and macrophage-activating effect (Kim et al, 2013), are associated with the phenol content in the mulberry fruit (Donno, Cerutti, Prgomet, Mellano, & Beccaro, 2015;Ercisli & Orhan, 2007;Khan et al, 2013) and non-anthocyanin polyphenols (Dilip & Tetsuya, 2007;Farrell, Norris, Lee, Chun, & Blesso, 2015;Liang et al, 2012). As a major type of active flavonoid, rutin functions to reduce capillary fragility, improve microcirculation and can be used to treat diabetes mellitus, hypertension, hyperglycemia and other disorders (Duarte, Carvalho, Gadelha, & Braga, 2014;Fernandes et al, 2010).…”

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confidence: 99%

Partial‐least‐squares and canonical‐correlation analysis of chemical constituents and active ingredients of new types of Chinese mulberries

Sun

Chen

2018

Food Science & Nutrition

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ObjectiveTo investigate the correlation between chemical constituents and active ingredients of 13 types of Chinese mulberry fruits.MethodsThirteen types mulberry fruits were harvested. The correlation between chemical constituents and active ingredients (primarily anthocyanins and rutins) of 13 new types of Chinese mulberries was assessed using partial‐least‐squares, principle‐component and canonical‐correlation analyses.ResultsVitamin C and titratable acid in the mulberry fruits were critical components that affected the active ingredients, especially anthocyanins and rutins. The content of titratable acid content was related to the fruit flavor and maintained the balance of anthocyanins, vitamin C and rutins. Mineral elements, such as Zn and Cu, also played a vital role in these processes. Low contents of sugar, crude protein, crude fat and pectin were significantly correlated with the mineral elements.ConclusionChemical constituents and mineral elements can mutually affect the concentration. It provides a novel method for any changes in the quality of new types of Chinese mulberries, which can identify the sources of new types of natural antioxidants.

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“…The structure of anthocyanin molecules is simple and easily absorbed, with antioxidant, anti-inflammatory, and chemoprotective effects that reduce the risk of cardiovascular disease and cancer, with the ability to scavenge free radicals and prevent free radical damage [ 49 ]. Rutin is one of the main active flavonoids that can reduce capillary fragility and improve microcirculation and can treat diabetes, hypertension, hyperglycemia, and other diseases [ 50 ]. Quercetin and catechins and other polyphenols can improve host obesity associated with high-fat diets by modulating the gut microbiota [ 51 , 52 ].…”

Section: Resultsmentioning

confidence: 99%

Assessment of the Fruit Chemical Characteristics and Antioxidant Activity of Different Mulberry Cultivars (Morus spp.) in Semi-Arid, Sandy Regions of China

Sun,

Zhou,

Zhu

et al. 2023

Foods

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As a traditional cash crop with ecological and nutritional values, mulberry is gradually expanding its consumption worldwide due to its great regional adaptability and superior health functions. The widespread interest in nutrients has led to a growing need to explore in depth the health benefits of mulberries. Many studies are actively being conducted to investigate the adaptability of the diversity of mulberries in different applications. This study systematically investigated the physicochemical properties and antioxidant activity of four mulberry genotypes cultivated in China’s semi-arid sandy regions to better understand the composition and health-promoting potential of this super crop. Chemical composition identification was identified via HPLC and antioxidant activity was further determined via DPPH and FRAP. The moisture, crude protein, ash, soluble solids, phenolics, anthocyanins, and flavonoids contents of mulberry were comparatively analyzed. The study revealed that the four mulberry genotypes showed significant differences in quality and content of the analyzed characteristics. The greatest antioxidant activity was found in Shensang 1, which had the most soluble solids (17%) and the highest amounts of free sugar (fructose: 5.14% and glucose: 5.46%). Ji’an had the most minerals (K: 2.35 mg/g, Ca: 2.27 mg/g, and Fe: 467.32 mg/kg) and it also contained chlorogenic acid, which has the potential to be turned into a natural hypoglycemic agent. PCA and Pearson correlation analysis indicated that the antioxidant activity was closely related to the chemical contents of total phenols, flavonoids, anthocyanins, and soluble sugars. If the antioxidant activity and nutrient content of the developed plants are considered, Shen Sang 1 is the most favorable variety. This finding can be used to support the widespread cultivation of mulberries to prevent desertification as well as to promote the development of the mulberry industry.

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Rutin reduces oxidative stress in animals with renovascular hypertension

Cited by 6 publications

References 0 publications

Genome-wide identification, phylogeny, evolutionary expansion and expression analyses of bZIP transcription factor family in tartary buckwheat

Genome-wide identification, phylogeny, evolutionary expansion and expression analyses of bZIP transcription factor family in tartary buckwheat

Partial‐least‐squares and canonical‐correlation analysis of chemical constituents and active ingredients of new types of Chinese mulberries

Assessment of the Fruit Chemical Characteristics and Antioxidant Activity of Different Mulberry Cultivars (Morus spp.) in Semi-Arid, Sandy Regions of China

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