“…Multiplebiological activities including the anti-oxidant (Yang, Yang, & Zheng, 2010), hypolipidemic effect (Liu et al, 2009), and macrophage-activating effect (Kim et al, 2013), are associated with the phenol content in the mulberry fruit (Donno, Cerutti, Prgomet, Mellano, & Beccaro, 2015;Ercisli & Orhan, 2007;Khan et al, 2013) and non-anthocyanin polyphenols (Dilip & Tetsuya, 2007;Farrell, Norris, Lee, Chun, & Blesso, 2015;Liang et al, 2012). As a major type of active flavonoid, rutin functions to reduce capillary fragility, improve microcirculation and can be used to treat diabetes mellitus, hypertension, hyperglycemia and other disorders (Duarte, Carvalho, Gadelha, & Braga, 2014;Fernandes et al, 2010).…”