Ruthenium Nanoparticles Uniformly‐designed Chemically Treated Graphene Oxide Nanosheets for Simultaneous Voltammetric Determination of Dopamine and Acetaminophen

Abstract

A new nanocomposite based on ruthenium nanoparticles (RuNPs) uniformly designed at chemically treated graphene oxide nanosheets (CTGONS) was prepared as active electrode for simultaneously sensing of dopamine (DA) and acetaminophen (AC) in the presence of high concentration of ascorbic acid (AA). The RuNPs actively decorates the CTGONS with uniform dispersion like pump sputtering of paints. The CTGONS of hexagonal nanosheets, 2D orientation, chemically treated to the reduced forms and active decoration by RuNPs lead to formation of high catalytic active sites and high loading of targets at the electrode surface. The suitable accommodation of RuNPs/CTGONS to fast response of targets ascertains a high catalytic activity, and fast charge transport. The RuNPs/CTGONS nanocomposite shows an obvious catalytic oxidation signal for DA and AC. The highly sensitive and selective electrode was designed based on RuNPs/CTGONS due to the large peak potentials separation of DA to AC of 0.22 V with sufficient electron mediating behavior. Moreover, the nanocomposite electrode shows individual and simultaneous determination of DA and AC with linear calibration plots from 5-120 μM and 10-120 μM, where their detection limits were calculated to be 0.018 � 0.002 and 0.023 � 0.003 μM, respectively. Finally, the analytical application of the RuNPs/CTGONS electrode was applied for the determination of DA and AC in the serum of human blood.

Silver nanowire size‐dependent effect on the catalytic activity and potential sensing of H2O2

“…The catalytic activity was increased with a decrease of AgNWs diameter, due to the large surface area of AgNWs0.05. [ 47 ]…”

Non-metal sensory electrode design and protocol of DNA-nucleobases in living cells exposed to oxidative stresses

“…This result was confirmed by studying the scan rate effect on the anodic signaling of 20 µM Ad. By plotting the square root of scan rate versus the anodic peak current, a linear relationship is obtained with a regression equation of I (µA) = -63.7 + 0.046 ν (mVs -1 ), R 2 = 0.995 (Figure 3[H&K]) [15,60,61].…”

Graphite Studded with Facile-Synthesized Cu2O Nanoparticle-Based Cubes as a Novel Electrochemical Sensor for Highly Sensitive Voltametric Determination of Mebeverine Hydrochloride

“…The low value of % RSD indicates the good precision and accuracy of the method. The lower limit of detection (LOD) and quantification (LOQ) were calculated using the following two equations: LOD = 3σ/b and LOQ = 10σ/b, where σ is the standard deviation of the intercept and b is the slope of the calibration curve [13,14,34,[40][41][42]. The calculated values of LOQ and LOQ for ten repeated quantifications of MEB and related regression data of the elaborated calibration plot are presented in Table 2.…”

“…Carbon-based metal nanoparticles have attracted considerable attention due to their mechanical and thermal properties and their ability for electrode modifications [13,14]. Because of these properties, metal and metal oxide nanoparticles have been used successfully for increasing carbon paste electrode sensitivity toward various electroanalytical applications [15,16].…”