“…To our delight, the desired product 1 was obtained in 92% yield (Scheme 3) in the presence of [Ru ( p-cymene)Cl 2 ] 2 (5 mol%), AgNTf 2 (20 mol%), and NaOAc (50 mol%) in DCE (0.1 M) at 80 °C under nitrogen for 12 h. Subsequently, under the optimized conditions, C-nucleoside analogs (Scheme 3) were synthesized from benzimidates and dioxazolone glycogen anomers. This approach was applicable to many substituted alkyl benzimidates containing electronneutral (5,6,16,17), electron-withdrawing (2-4, 9-15), and electron-donating (7,8,19) groups, resulting in the corresponding 2-glycosyl-quinazolines in moderate to excellent yields. It is noteworthy that esters (9-11), halogens (2-4, 13, 14), and benzyloxy (7) groups exhibited tolerance, thereby providing promising prospects for subsequent functionalizations.…”