Ruptured anterior mediastinal teratoma with radiologic, pathologic, and bronchoscopic correlation

Escalon, Joanna G.; Arkin, Jordan E.; Chaump, Michael; Harkin, Timothy J.; Wolf, Andrea; Legasto, Alan C.

doi:10.1016/j.clinimag.2015.03.007

Cited by 7 publications

(9 citation statements)

References 9 publications

(12 reference statements)

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“…In addition to these findings, the presence of internal inhomogenous densities within the mass, irregular tumor margins and bursting configuration of fat globules should raise the possibility of rupture[ 23 , 24 ]. It is important for radiologists to identify these signs of rupture and guide clinicians in planning proper surgical management[ 25 ].…”

Section: Cystic Thymic Massesmentioning

confidence: 99%

Imaging of the pediatric thymus: Clinicoradiologic approach

Manchanda¹,

Bhalla²,

Jana³

et al. 2017

WJCP

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The thymus is a lymphatic organ that undergoes dynamic changes with age and disease. It is important to be familiar with these physiological changes in the thymus gland to be able to identify pathology and make an accurate diagnosis. The thymus may be involved in multisystem disorders or show focal isolated lesions. The aim of this article is to review the radiological anatomy of the thymus, normal variants, and pathology including hyperplasia and benign/malignant lesions involving the thymus gland in the pediatric age group. We also propose an algorithmic approach for imaging evaluation of a suspected thymic mass on the basis of morphologic features.

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Section: Cystic Thymic Massesmentioning

confidence: 99%

Imaging of the pediatric thymus: Clinicoradiologic approach

Manchanda¹,

Bhalla²,

Jana³

et al. 2017

WJCP

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“…Approximately 36% of all mediastinal teratomas are associated with rupture that is most frequently spontaneous in nature and can result in significant symptoms including severe chest pain, hemoptysis, fever, and severe respiratory distress [ 3 , 5 , 6 ]. It is hypothesized that spontaneous rupture is the result of digestive and proteolytic enzymes released from pancreatic tissue, salivary gland tissue, or intestinal epithelium [ 3 – 6 ]. Pancreatic tissue acts as a source of proteolytic enzymes and is commonly found in benign mature teratomas, which makes them more frequently associated with rupture than other teratomas [ 2 , 3 , 6 ].…”

Section: Discussionmentioning

confidence: 99%

“…It is hypothesized that spontaneous rupture is the result of digestive and proteolytic enzymes released from pancreatic tissue, salivary gland tissue, or intestinal epithelium [ 3 – 6 ]. Pancreatic tissue acts as a source of proteolytic enzymes and is commonly found in benign mature teratomas, which makes them more frequently associated with rupture than other teratomas [ 2 , 3 , 6 ]. This may correlate with the elevated serum CA 19-9 seen preoperatively in our patient.…”

Section: Discussionmentioning

confidence: 99%

“…Other causes of spontaneous rupture can be attributed to sebaceous secretions within the cyst, which can weaken the cyst wall and lead to rupture [ 1 , 5 , 6 ]. Infection can lead to rupture by increasing the fragility of the cyst wall [ 1 , 5 , 6 ]. Necrosis secondary to ischemia from rapidly expanding tumors has also resulted in spontaneous rupture [ 1 , 5 , 6 ].…”

Section: Discussionmentioning

confidence: 99%

“…Infection can lead to rupture by increasing the fragility of the cyst wall [ 1 , 5 , 6 ]. Necrosis secondary to ischemia from rapidly expanding tumors has also resulted in spontaneous rupture [ 1 , 5 , 6 ]. Although some or all of these mechanisms may have caused an increased susceptibility for tumor rupture in our patient, very few reports have named trauma as the definitive cause of teratoma rupture as illustrated in this case [ 1 , 7 , 8 ].…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Traumatic Rupture of A Posterior Mediastinal Teratoma following Motor-Vehicle Accident

Bell

Domingo

Miller

et al. 2016

Case Reports in Surgery

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We report a case of a posterior mediastinal mature cystic teratoma with rupture secondary to blunt chest trauma in a 20-year-old male involved in a motor-vehicle accident. Initial treatment was guided by Advanced Trauma Life Support and a tube thoracostomy was performed for presumed hemothorax. The heterogeneous collection within the thoracic cavity was discovered to be the result of a ruptured cystic mass. Pathologic findings confirmed the mass consistent with a mature cystic teratoma. As mediastinal teratomas are most commonly described arising from the anterior mediastinum, the posterior location of the teratoma described in this report is exceedingly rare.

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Teratoma

2016

Specialty Imaging: Thoracic Neoplasms

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Ruptured anterior mediastinal teratoma with radiologic, pathologic, and bronchoscopic correlation

Cited by 7 publications

References 9 publications

Imaging of the pediatric thymus: Clinicoradiologic approach

Imaging of the pediatric thymus: Clinicoradiologic approach

Traumatic Rupture of A Posterior Mediastinal Teratoma following Motor-Vehicle Accident

Teratoma

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