Rue the Herb: Ruta Graveolens Associated Phytophototoxicity

Eickhorst, Kimberly M.; DeLeo, Vincent A.

doi:10.1097/01206501-200506000-00009

Cited by 3 publications

(3 citation statements)

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“…The most notable species in this family is the fig tree, Ficus carica, which is native to the Middle East. Psoralens are found chiefly in the stem and leaves 1,2 . A number of factors such as geographical location, seasonal variations, humidity and plant fungal infections can alter the level of furocoumarin in a given plant.…”

Section: Discussionmentioning

confidence: 99%

Phytophotodermatitis: an occupational and recreational skin disease

Moreira

Leite

Guedes

et al. 2010

Rev. Assoc. Med. Bras.

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Case 1A 45 year old woman presented with erythema and large fluidfilled blisters on both legs. She was a rural worker and four days before had been harvesting rue (Ruta graveolens) with continuous exposure to sunlight. The lesions had the typical linear arrangement (Figure 1). She was treated with antihistamines, topical and oral corticosteroids. Residual hyperpigmentation was seen two weeks later. Case 2A 56 year old woman, rural worker, was referred for evaluation of erythematous plaques, edema, vesicles and blisters on her left hand, forearm and arm (Figure 2). It was not possible to determine the responsible sensitizer plant, as the patient had come in contact with numerous plants. The same kind of treatment as in the previous case was instituted with severe hyperpigmented patches. Case 3A 49 year old male, recreational fisher was admitted with dusky erythematous plaques and bullae in a linear pattern on his forearms. Three days before he had been fishing near a mossy wall. It was not possible to determine the exact offending plant. He was treated in the same way as above and ten days later the lesions had completely healed without scarring.

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Section: Discussionmentioning

confidence: 99%

Phytophotodermatitis: an occupational and recreational skin disease

Moreira

Leite

Guedes

et al. 2010

Rev. Assoc. Med. Bras.

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“…Hyperpigmentation occurs over 1 to 2 weeks and can persist for 6 to 12 months. 33 The incidence of phototoxic reaction and the frequency of reactions to drugs used in childhood are unknown. In all likelihood, the most common drugs responsible for this type of reaction in pediatric patients are antibiotics, including sulfonamides, quinolones, and tetracyclines.…”

Section: Drug-and Chemical-induced Photosensitivitymentioning

confidence: 99%

Photosensitivity disorders in children

Chantorn

Lim

Shwayder

2012

Journal of the American Academy of Dermatology

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“…PPD is a phototoxic reaction entirely independent from the immune system. This reaction occurs when the skin is exposed to photosensitizer substances and to ultraviolet radiation, different from the photoalergic reactions, in which there is an immunologic component [3,4,7,8] . When a photon with appropriate wavelength joins a psoralen, it is absorbed, releasing energy, it is not clear if in the form of heat, fluorescence (ability of one compound to react to ultraviolet rays) or phosphorescence (ability of a chemical species to emit light), forming what is called a photo-product.…”

Section: Phytophotodermatitismentioning

confidence: 99%

Phytophotodermatitis: A Review of Its Clinical and Pathogenic Aspects

Almeida

Sartori

Jorge³

et al. 2016

Journal of Dermatological Research

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Phytodermatoses are diseases caused by the contact of human beings with plants. Phytophotodermatitis is a phototoxic reaction entirely independent from the immune system. This reaction occurs when the skin is exposed to photosensitizer substances and to ultraviolet radiation, different from the photoalergic reactions, in which there is an immunologic component. Phytophotodermatitis has a wide range of clinical presentations, the hands are the most common localisation. The Tahiti lemon is the most common cause in Brazil. Experimental researches in animals showed that after 24 hours there are histological changes, characterized by vacuolization and keratinocyte necrosis, which evolves to blister formation after 48 hours, when clinically erythema and blisters could be seen. The initial lesion occurs in the cell membrane and in the desmosomes.

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Rue the Herb: Ruta Graveolens Associated Phytophototoxicity

Cited by 3 publications

References 0 publications

Phytophotodermatitis: an occupational and recreational skin disease

Phytophotodermatitis: an occupational and recreational skin disease

Photosensitivity disorders in children

Phytophotodermatitis: A Review of Its Clinical and Pathogenic Aspects

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