“…Robson et al (1965) have suggested that some asthmatic patients may have a constitutionally subnormal adrenocortical function, and it would seem that in this group of patients corticotrophin would be particularly indicated. Svedmyr (1969) has investigated the in vitro effect of natural and synthetic human corticotrophin on human smooth musculature. A dose‐response relationship in muscle relaxation could be shown which may represent a direct extraadrenal effect of corticotrophin.…”