Rubella

Horstmann, Dorothy M.

doi:10.1007/978-1-4613-3988-5_19

Cited by 6 publications

(2 citation statements)

References 98 publications

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“…Table 4 shows that vaccination in the puerperium gives a similar incidence of immunity when assessed at a serum dilution of 1/16 to that seen in the United Kingdom born population (Table 3). However, when assessed at 1/64, a level of antibody believed to confer substantial immunity (Horstman, 1976), comparison with the general population shows a significant difference (X2 fourfold test P < 0.001).…”

Section: Pregnantmentioning

confidence: 87%

Susceptibility to rubella in a pregnant population after the introduction of vaccination.

Broadbent¹,

Ajina²,

Hurley³

1980

J Clin Pathol

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Section: Pregnantmentioning

confidence: 87%

Susceptibility to rubella in a pregnant population after the introduction of vaccination.

Broadbent¹,

Ajina²,

Hurley³

1980

J Clin Pathol

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“…The rate of vertical transmission was found to drop to 25% in the late second trimester. However, the rate might increase to 35% around 27–30 weeks and rises to approximately 100% at 36 weeks of gestation [ 12 , 13 , 14 ].…”

Section: Introductionmentioning

confidence: 99%

Reduction in Rubella Virus Active Cases among Children and Adolescents after Rubella Vaccine Implementation in Tanzania: A Call for Sustained High Vaccination Coverage

et al. 2022

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Rubella virus (RV) infection in susceptible women during the first trimester of pregnancy is associated with congenital Rubella syndrome (CRS). In countries where a vaccination program is implemented, active case surveillance is emphasized. This report documents the magnitude of active cases before and after vaccine implementation in Tanzania. A total of 8750 children and adolescents with signs and symptoms of RV infection were tested for Rubella IgM antibodies between 2013 and 2019 using enzyme immunoassay followed by descriptive analysis. The median age of participants was 3.8 (IQR: 2–6.4) years. About half (4867; 55.6%) of the participants were aged 1–5 years. The prevalence of RV active cases was 534 (32.6%, 95% CI: 30.2–34.9) and 219 (3.2%, 95% CI: 2.7–3.6) before and after vaccine implementation, respectively. Before vaccination, the highest prevalence was recorded in Pemba (78.6%) and the lowest was reported in Geita (15.6%), whereas, after vaccination, the prevalence ranged between 0.5% in Iringa and 6.5% in Pemba. Overall, >50% of the regions had a >90% reduction in active cases. The significant reduction in active cases after vaccine implementation in Tanzania underscores the need to sustain high vaccination coverage to prevent active infections and eventually eliminate CRS, which is the main goal of Rubella vaccine implementation.

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Rubella Virus and its Effects on the Developing Nervous System

Wolinsky¹

1988

Virus Infections and the Developing Nervous System

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Rubella

Cited by 6 publications

References 98 publications

Susceptibility to rubella in a pregnant population after the introduction of vaccination.

Susceptibility to rubella in a pregnant population after the introduction of vaccination.

Reduction in Rubella Virus Active Cases among Children and Adolescents after Rubella Vaccine Implementation in Tanzania: A Call for Sustained High Vaccination Coverage

Rubella Virus and its Effects on the Developing Nervous System

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