volume 3, issue 2, P138-142 2012
DOI: 10.5155/eurjchem.3.2.138-142.537
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Abstract: A simple, sensitive and precise high performance liquid chromatographic method for the analysis of atenolol and indapamide with UV detection at 231 nm, has been developed, validated and used for the determination of these compounds in pharmaceutical dosage forms, in human blood and in human milk. The compounds were well separated on a Hypersil BDS C18 reversed-phase column with mobile phase consisting of, pH = 3.5, 0.01 M potassium dihydrogen orthophosphate buffer-acetonitrile (60:40; v:v) at a flow rate of 1…

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