Routine Primary PCI; Whether and When Necessary for the Management of NSTEMI—An Evidence Based Evaluation

Hasan, Irtiza; Rashid, Tasnuva; Bhuiyan, Md. Harun Ur Rashid

doi:10.4236/wjcd.2015.512040

Cited by 3 publications

(2 citation statements)

References 19 publications

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“…13 Sementara itu, pasien yang datang antara 12 hingga 48 jam setelah timbulnya gejala, bahkan jika tanpa angina dan dengan hemodinamik yang stabil, dikatakan masih mendapat manfaat dari angiografi koroner dini dan mungkin PCI. 13,17,18 Penelitian dari Schömig…”

Section: Diskusiunclassified

Waktu antara angina dan tindakan percutaneous coronary intervention menyebabkan perubahan wall motion score index pada pasien infark miokard akut

Sari¹

2018

medicina

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Blockage due to thrombus in Acute Myocardial Infarction (AMI) causes complete ischemia and necrosis in areas supplied by blocked arteries. Rapid revascularization with Percutaneous Coronary Intervention (PCI) will decrease myocardial damage. The left ventricle function is an important outcome during PCI. A semi-quantitative assessment of the regional left ventricular contractile function can be obtained through the assessment of the Wall Motion Score Index (WMSI). The time between angina and PCI is most important, since the time lag represents the total ischemic time, so it needs to be reduced to the shortest possible to increase the clinical outcome. This study aimed to know the correlation between WMSI changes between patients who were treated with PCI with shorter total ischemic time compare with longer total ischemic time. This was a cohort prospective study conducted in Sanglah Hospital, Denpasar, Bali, during November 2017 until January 2018. This study included 32 AMI patients who are treated with PCI. WMSI was measured using transthoracic echocardiography before and 72 hours after PCI. From ROC curve analysis, the time cutoff point between angina and PCI action was 313 minutes with 75% sensitivity and 54% specificity and there were 2 groups consist of group with the time integral between angina and PCI less than 313 minute (early group) and group with the time integral between angina and PCI more than equal to 313 minute (late group). By using the Wilcoxon sign rank pair test, there was significant WMSI changes in both early and late groups before and 72 hours after PCI, with the early group showed better improvement compared to the late group. Meanwhile, Wilcoxon Mann Whitney U test result showed that there was no significant difference in WMSI changes in the early group compared to the late group. These result showed the importance of PCI in improving myocardial contractility even in patients who underwent PCI later than 5 hours after the onset of chest pain.

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Section: Diskusiunclassified

Waktu antara angina dan tindakan percutaneous coronary intervention menyebabkan perubahan wall motion score index pada pasien infark miokard akut

Sari¹

2018

medicina

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“…HF is a major public health issue with substantial mortality and morbidity which also poses a challenge to clinical diagnosis and generally affects the older segment of the population [4] [5]. Various clinical conditions including ischemic and non-ischemic heart diseases, metabolic and endocrine diseases, infectious and chronic diseases, use of cardiac and non-cardiac cardiotoxic drugs are some of the common factors causing HF [6]- [11]. The prevalence of HF has an increasing trend with 23 million people worldwide being affected in 2011 alone [4].…”

Section: Introductionmentioning

confidence: 99%

NYHA Class II or III Heart Failure: Who Will Need an Implantable Cardioverter Defibrillator (ICD)?

Hasan¹,

Hossain²,

Bhuiyan³

2016

WJCD

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Sudden cardiac death (SCD) is one of the most debilitating and life-threatening complications of heart failure (HF) which has challenged medical care for long. Current guidelines suggest the use of Implantable Cardioverter Defibrillator (ICD) in primary prevention of SCD in both New York Heart Association (NYHA) class II and class III heart failure. This paper critically evaluated the evidence underlying the guideline recommendation. In contrast to recent guidelines, the majority of the intervention trials conducted on the topic till date found a promising role of ICD only in the prevention of SCD in NYHA class II HF. One of the trials which found a significant role of ICD in type III heart failure was underpowered. Thus, further trials are needed to validate the use of ICD in the prevention of SCD in type III HF.

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A Critical Evaluation of the Role of Routine Uses of Statin as a Tool for Primary Prevention of Cardiovascular Diseases

Hasan¹,

Rashid²,

Bhuiyan³

2016

OJPM

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Use of Statin is a cornerstone in modern day medical practice and an essential component for primary prevention of cardiovascular diseases (CVD). Various evidences exemplify and resonate the importance of Statins in reducing CVD mortality and improvement of survivability. However, there is a continental variation in recent guidelines directing lipid-lowering therapy in regards to aim, dose, timing as well as the protocol for initiation of therapy. Similar uncertainties exist with regards to the generalizability of the finding from available evidence, a variation of benefits of Statin with respect to age and gender, the validity of the research conducted and actual gain in survivability and mortality benefits. Thus, there is a need for looking at the actual indications, riskbenefit ratios and cost effectiveness before tediously prescribing Statin for the primary prevention of CVDs. This paper will attempt to critically review the evidence behind the uses of Statins in the primary prevention of CVDs.

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Routine Primary PCI; Whether and When Necessary for the Management of NSTEMI—An Evidence Based Evaluation

Cited by 3 publications

References 19 publications

Waktu antara angina dan tindakan percutaneous coronary intervention menyebabkan perubahan wall motion score index pada pasien infark miokard akut

Waktu antara angina dan tindakan percutaneous coronary intervention menyebabkan perubahan wall motion score index pada pasien infark miokard akut

NYHA Class II or III Heart Failure: Who Will Need an Implantable Cardioverter Defibrillator (ICD)?

A Critical Evaluation of the Role of Routine Uses of Statin as a Tool for Primary Prevention of Cardiovascular Diseases

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