Roundworms in Fishes and so-called "Herring-worm Disease"

Abstract

Raynaud's Phenomenon-;ohnston et al. bEDICAmJOURA from the finger-tips, especially if associated with resorption of the terminal phalanges, points towards some other disease process, in particular systemic scleroderma.Flat (macular) polygonal telangiectases on the hands are unusual in patients with Raynaud's phenomenon. In this series they occurred in the patients with systemic scleroderma, and in very small numbers (one to three) in five patients with confirmed primary Raynaud's phenomenon. We believe that in patients with Raynaud's phenomenon, macular telangiectases may be the most valuable early clinical sign of incipient or overt systemic scleroderma if present on the hands, but are of less significance if found on the face alone.Brachial arteriography is not helpful in distinguishing severe primary Raynaud's phenomenon from early systemic scleroderma. This procedure was performed pre-operatively on four of the patients initially diagnosed as having primary Raynaud's phenomenon who later developed systemic scleroderma. In two the arteriograms were normal, and in two digital-arterial blocks were demonstrated, but there was no specific radiological change to indicate that systemic scleroderma would ensue. Apart from this, arteriography affords a reliable method of diagnosing digital-arterial blockage and was used in the pre-operative assessment of a total of 15 of our patients.In the 727 patients' suffering from systemic scleroderma reviewed by Tuffanelli and Winkelmann (1961) Eight patients apparently suffering from primary Raynaud's phenomenon at the time of operation had developed systemic scleroderma at follow-up, the Raynaud's phenomenon preceding other features of the disease by an interval of from 3 to 20 years.The late results of sympathectomy were best in digital-artery thrombosis (71 % success) and in confirmed primary Raynaud's phenomenon (58 % success). The results were poor in patients who had advanced systemic scleroderma at the time of operation and in the three patients who had other connective-tissue disorders, but no dissemination of the condition resulted from operation.The patients with apparent primary Raynaud's phenomenon who ultimately developed systemic scleroderma responded to sympathectomy; the operative result gave no indication of the true diagnosis. In such patients finger-tip necroses and macular telangiectases on the hands should suggest incipient systemic scleroderma.

Eosinophilic granuloma of the gastro-intestinal tract.

“…These cases all presented as an acute abdomen and were found to have eosinophilic granulomata of the bowel associated with a larval roundworm normally found in the North Sea herring. Exact identification of the larval roundworm is difficult at present (Williams, 1965). Members of the Gnathostomidae, Ancylostomidae, Ascaridae, and Anisakidae can also cause eosinophilic granuloma (Freeman, 1964).…”

EALIKLARDAN İNSA1\'LARA GEÇERiLEN HASTALIKLAR

“…Anisakis tipi larvalar insanlarda akut abdominal syndromu olu~turmaktadır (27). Hollanda'da yapılan bir ara~tırmada buna benzeyen ve deniz balıklarının nematodu olan Eustoma'nın insanlarda aynı syndromu yaptığı gÖ3terilmi~tir (27). Ascarid nematod'larının üçüncü dönem larvaları, çiğ veya çok az tuzlanmı~deniz balıklarının yenilmesiyle insanlarda enfeksiyon olu~turabilmektedirler (I 8).…”

“…Ascarid nematod'larının üçüncü dönem larvaları, çiğ veya çok az tuzlanmı~deniz balıklarının yenilmesiyle insanlarda enfeksiyon olu~turabilmektedirler (I 8). İnsanlarda Anisakis türündeki larva enfeksiyonları yanısıra, Phoeanema ve Contraeaeeum türünde bulunan para"':itlerde önemli para7itik enfeksiyonlara neden olabilmektedirler (27). İnsanlarda eri~kin~ekledönü~meyen nematocilar mide duvarında eosinophilic granuloma yapmaktadırlar, Dünyanın hemen her tarafında göı'ıilen bu türdeki patolojik bpzukluklara Japonya'da sıkça raslanılmaktadır (2 ı).…”

The laboratory diagnosis of tropical diseases with special reference to Britain: a review.

“…Examples of this situation are tropical pulmonary eosinophilia usually due to some form of filaria; the closely related Loeffler's syndrome which may be due to Strongyloides; visceral larva migrans of which the prototype is Toxocara canis (Woodruff, 1970); cutaneous larva migrans due to canine or other Ankylostoma; eosinophilic phlegmon of the gut due to Anisakis (Ashby, Appleton, and Dawson, 1964;Williams, 1965); and dermatitis due to zoonotic forms of schistosomiasis, which has been reported in Britain (Knight and Worms, 1972).…”