Rotterdam and Brussels CT-based neck nodal delineation compared with the surgical levels as defined by the American Academy of Otolaryngology–Head and Neck Surgery
“…17,18 It is likely that with the increasing use of biological targeting, this issue will become even more complex in the future. 19 Lastly, a recent article also suggested that significant variations between prescribed dose and delivered dose may have implications regarding disease outcome after IMRT. 20 The aforementioned uncertainties attest to the paramount importance of accurate patient setup and immobilization when delivering IMRT for head and neck cancer.…”
“…17,18 It is likely that with the increasing use of biological targeting, this issue will become even more complex in the future. 19 Lastly, a recent article also suggested that significant variations between prescribed dose and delivered dose may have implications regarding disease outcome after IMRT. 20 The aforementioned uncertainties attest to the paramount importance of accurate patient setup and immobilization when delivering IMRT for head and neck cancer.…”
“…Guidelines for the delineation of the various node levels in the neck have also been proposed, and a series of consensus recommendations endorsed by major North American (Radiation Therapy Oncology Group [RTOG]) and European (Danish Head and Neck Cancer, European Organization for Research and Treatment of Cancer, Groupe d'Oncologie Radiothérapie Tête et Cou) cooperative groups has been elaborated for the N0 neck [15,16]. For the node-positive and the postoperative neck, further recommendations have been recently proposed [17,18].…”
Section: Challenge Of Selection and Delineation Of The Target Volumesmentioning
After completing this course, the reader will be able to:1. Outline innovations related to targeted radiation therapy.2. Describe trials proving an advantage using IMRT.3. Assess treatment planning modalities and how IMRT fields are designed.4. Evaluate when there is a toxicity advantage for IMRT.5. Discern when conventional radiotherapy should be used instead of IMRT.Access and take the CME test online and receive 1 AMA PRA Category 1 Credit ™ at CME.TheOncologist.com CME CME ABSTRACT Intensity-modulated radiation therapy (IMRT) for head and neck tumors refers to a new approach that aims at increasing the radiation dose gradient between the target tissues and the surrounding normal tissues at risk, thus offering the prospect of increasing the locoregional control probability while decreasing the complication rate. As a prerequisite, IMRT requires a proper selection and delineation of target volumes. For the latter, recent data indicate the potential of functional imaging to complement anatomic imaging modalities. Nonrandomized clinical series in paranasal sinuses and pharyngolaryngeal carcinoma have shown that IMRT was able to achieve a very high rate of locoregional control with less morbidity, such as dry-eye syndrome, xerostomia, and swallowing dysfunction. The promising results of IMRT are likely to be achieved when many treatment conditions are met, for example, optimal selection and delineation of the target volumes and organs at risk, appropriate physical quality control of the irradiation, and accurate patient setup with the use of onboard imaging. Because of the complexity of the various tasks, it is thus likely that these conditions will only be
“…For each patient two or three different volumes were defined. CTV1 (clinical target volume) included the regional nodes at risk and was defined according to published criteria for selection and delineation of the neck nodes [10,11,18,20]. CTV2 included only the macroscopic nodes (defined only for three patients).…”
HT improves the homogeneity of dose distribution within PTV and PTV coverage together with a significantly greater sparing of OARs compared to linac five-field IMRT.
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