2007
DOI: 10.1007/s00066-007-1698-x
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Simultaneous Integrated Boost (SIB) for Nasopharynx Cancer with Helical Tomotherapy

Abstract: HT improves the homogeneity of dose distribution within PTV and PTV coverage together with a significantly greater sparing of OARs compared to linac five-field IMRT.

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Cited by 63 publications
(44 citation statements)
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“…Vanetti et al ( 12 ) observed that normalRA2 improved the homogeneity of dose distribution within PTV and PTV coverage together with a significantly greater sparing of OARs, compared with conventional IMRT and normalRA1 (single RapidArc). ( 61 ) …”
Section: Discussionmentioning
confidence: 99%
“…Vanetti et al ( 12 ) observed that normalRA2 improved the homogeneity of dose distribution within PTV and PTV coverage together with a significantly greater sparing of OARs, compared with conventional IMRT and normalRA1 (single RapidArc). ( 61 ) …”
Section: Discussionmentioning
confidence: 99%
“…However, these improvements in outcome come at the cost of increased acute as well as late toxicity [14,16]. Recently, the introduction of intensity-modulated radiotherapy (IMRT) has considerably reduced toxicity for various tumor sites [7,27]. Clearly, the organ-sparing potential of IMRT and other highly conformal radiotherapy techniques relies heavily on the appropriate selection and accurate delineation of the critical organs at risk (OARs), with the application of rigorous constraints during planning [5,28].…”
Section: Introductionmentioning
confidence: 99%
“…The purpose was to explore the potential of tomotherapy as a new method of image-guided intensity-modulated radiotherapy (IMRT) to lower the dose to kidneys, liver and bone marrow while covering the peritoneal cavity with a homogeneous dose [8,15,16,23,24]. With a field width of 40 cm and a maximal length of 160 cm, helical tomotherapy is a very promising option for this kind of large and complexly shaped target volumes [1,2,6,10,12,17,19]. We provide the first clinical report on the use of tomotherapy in large-field WAI.…”
Section: Introductionmentioning
confidence: 99%