Rotavirus genotype trends from 2013 to 2018 and vaccine effectiveness in southern Vietnam

Associations between meteorological variation and hospitalisations for rotavirus infections in Kuala Lumpur, Malaysia

“…In contrast, Mejiozem et al [ 19 ] concluded that lower rainfall levels and higher temperatures were associated with the highest prevalence of RoV-induced diarrhoea. This is supported by a study conducted in Vietnam, which observed a statistically significant difference in RoV detection between the dry and rainy seasons and indicated that RoV was more frequently detected during the dry season compared to the rainy season [ 20 , 21 ].…”

Prediction of effectiveness of universal rotavirus vaccination in Southwestern Vietnam based on a dynamic mathematical model

“…Additionally, we already reported that the RVGE hospitalization rate was lower in the southeastern region of Vietnam, which has a higher socioeconomic status, including a higher GDP and a lower child mortality rate, than in the southwestern region. These findings emphasize the importance of improving both public health and sanitation, as well as socioeconomic status, to reduce the burden of RVGE 5 .…”

“…We set the hospitalization proportion by combining the results of the Ho Chi Minh City and Dong Thap regions investigated in a previous study 39 . For estimation, we used an anonymized database of patients aged < 5 years admitted with acute gastroenteritis to Pediatric Hospital No.1 in Ho Chi Minh City, Vietnam, from January 2013 to December 2018 5 .…”

“…Globally, rotavirus (RV) infection remains the main cause of severe acute gastroenteritis in children < 5 years of age, and the majority of fatalities occur in low- and middle-income countries (LMICs) 1 – 5 . RV vaccination is known to be the best preventive measure for reducing RV-associated morbidity and mortality 6 , but vaccine effectiveness (VE) is affected by several factors such as age, geographical location, seasonality, nutritional status, breastfeeding, co-existing enteropathy, and distribution dynamics of RV genotypes 2 , 7 – 10 .…”

“…Vietnam is one of the countries with a high disease burden of RV infection, but the RV vaccine has not been included in Vietnam's NIP up to October 2022, despite the presence of initial comprehensive multi-year plans. We recently reported the epidemiology of rotavirus gastroenteritis (RVGE) and RV VE in Southern Vietnam between 2013 and 2018 5 . In this hospitalization-based surveillance data, we found that RV vaccine coverage was low (4%), and the overall VE was as low as 59–70%.…”