Rotavirus Gastroenteritis Among Children Under Five Years of Age in Valencia, Spain

Abstract

The population-based incidence of rotavirus gastroenteritis in children <5 years of age in Valencia, Spain, over a 1-year period (December 1, 2003, to November 30, 2004) was determined.A total of 553 episodes of gastroenteritis in children <5 years of age (mean age, 22.8 +/- 14.5 months) were recorded (annual incidence of 138 per 1,000). A positive enzyme-linked immunoadsorbant assay result for rotavirus antigen was obtained in 15% of the samples. The incidence of rotavirus gastroenteritis was 15 per 1,000 children <5 years of age, being the highest incidence in children <or=12 months of age (31 per 1,000). Eighty percent of rotavirus gastroenteritis occurred during the winter months (January-March). Genotype G1 was detected in 86% of the samples and G4 in the other 14%.

An estimation of indirect costs caused by acute rotavirus gastroenteritis in a Galician area, Spain

“…According to the most recent epidemiological data about rotavirus disease in Spain, approximately 310,000 cases of rotavirus-induced diarrhea occur every year in children under 5 years of age, causing 7,500 hospitalizations [1][2][3][4]. If data collected from our study are used, only the indirect costs of rotavirus in patients requiring hospital admission would amount to 3.2 million euros every year.…”

A 4-year study on clinical characteristics of children hospitalized with rotavirus gastroenteritis

“…This was a 13-month-old boy with autoimmune hemolytic anemia and [6][7][8][9][10][11][12][13][14][15][16][17][18][19][20] and 519 (96.3%) patients had a score ≥11, generally considered as "severe disease" (Fig. 2).…”

“…Data about RV morbidity in Europe are available mainly for southern [2,9,26], northern [16,31], and western parts [1,3,6,11,28]. Only a few studies were performed in eastern Europe [22].…”

Circovirus and impact of temporary withdrawal of rotavirus vaccines in Spain

“…3 The incidence of rotavirus disease and the number of requests for primary care treatment in Spain is estimated at 38 cases per 1,000 infants under 1 year, 4 with hospitalizations at 6.5 per 1,000 <5 year, emergency care at 18.9 per 1,000 <5 year, and visits to health centers at 21.9 per 1,000 <5 year. 5,6 The average indirect cost of an episode of acute gastroenteritis caused by rotavirus is 194.6 euros (2010 update). 6 The direct medical cost is funded by the health service and according to the REVEAL study in Spain the average direct medical cost is estimated at 549 euros.…”

“…5,6 The average indirect cost of an episode of acute gastroenteritis caused by rotavirus is 194.6 euros (2010 update). 6 The direct medical cost is funded by the health service and according to the REVEAL study in Spain the average direct medical cost is estimated at 549 euros. 7 We have supposed a vaccine efficacy of 90.5% in patients who have received at least one dose of the vaccine and that vaccination coverage in Spain was 40%.…”