An estimation of indirect costs caused by acute rotavirus gastroenteritis in a Galician area, Spain

Martinón-Torres, Federico; Bouzón-Alejandro, Marta; López-Sousa, Maria; Redondo-Collazo, Lorenzo; Almeida-Agudín, Santiago; Astorgano-Fernández, Consuelo; Martinón-Sánchez, José María

doi:10.1007/s00431-007-0466-3

Cited by 18 publications

(11 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…A recent study[50] in the Galician area of Spain estimated that the mean indirect cost per case due to RVGE was €428. This cost included productivity loss, travel expenses, cost of caregivers, meals and materials.…”

Section: Discussionmentioning

confidence: 99%

Burden of paediatric Rotavirus Gastroenteritis (RVGE) and potential benefits of a universal Rotavirus vaccination programme with a pentavalent vaccine in Spain

Díez-Domingo¹,

Suriñach

Alcalde

et al. 2010

BMC Public Health

View full text Add to dashboard Cite

BackgroundRotavirus is the most common cause of gastroenteritis in young children worldwide. The aim of the study was to assess the health outcomes and the economic impact of a universal rotavirus vaccination programme with RotaTeq, the pentavalent rotavirus vaccine, versus no vaccination programme in Spain.MethodsA birth cohort was followed up to the age of 5 using a cohort model. Epidemiological parameters were taken from the REVEAL study (a prospective epidemiological study conducted in Spain, 2004-2005) and from the literature. Direct and indirect costs were assessed from the national healthcare payer and societal perspectives by combining health care resource utilisation collected in REVEAL study and unit costs from official sources. RotaTeq per protocol efficacy data was taken from a large worldwide rotavirus clinical trial (70,000 children). Health outcomes included home care cases, General Practioner (GP)/Paediatrician, emergency department visits, hospitalisations and nosocomial infections.ResultsThe model estimates that the introduction of a universal rotavirus vaccination programme with RotaTeq (90% coverage rate) would reduce the rotavirus gastroenteritis (RVGE) burden by 75% in Spain; 53,692 home care cases, 35,187 GP/Paediatrician visits, 34,287 emergency department visits, 10,987 hospitalisations and 2,053 nosocomial infections would be avoided. The introduction of RotaTeq would avoid about 76% of RVGE-related costs from both perspectives: €22 million from the national health system perspective and €38 million from the societal perspective.ConclusionsA rotavirus vaccination programme with RotaTeq would reduce significantly the important medical and economic burden of RVGE in Spain.

show abstract

Section: Discussionmentioning

confidence: 99%

Burden of paediatric Rotavirus Gastroenteritis (RVGE) and potential benefits of a universal Rotavirus vaccination programme with a pentavalent vaccine in Spain

Díez-Domingo¹,

Suriñach

Alcalde

et al. 2010

BMC Public Health

View full text Add to dashboard Cite

show abstract

“…12,13 The previous experience of the main team with a similar protocol, 14 the specific training of the participant subinvestigators distributed throughout the ©2 0 1 1 L a n d e s B i o s c i e n c e .…”

Section: Methodsmentioning

confidence: 99%

Effectiveness of rotavirus vaccination in Spain

Martinón-Torres¹,

Alejandro²,

Redondo-Collazo³

et al. 2011

Human Vaccines

Self Cite

View full text Add to dashboard Cite

“…Few previous studies in this setting were prospective, focused on indirect costs and included all types of patients from primary care to hospital care [18-21]. Only Lee et al have compiled such a comprehensive collection of indirect costs in the USA setting [21].…”

Section: Discussionmentioning

confidence: 99%

“…The REVEAL study considered both direct and indirect costs, and compiled data from 7 countries including Spain [20]. Another single centre hospital-based study performed by our group showed that the indirect costs generated by RVAGE were 2.6-fold higher than those induced by other etiologies [18,19]. …”

Section: Introductionmentioning

confidence: 99%

Prospective evaluation of indirect costs due to acute rotavirus gastroenteritis in Spain: the ROTACOST study

et al. 2011

Self Cite

View full text Add to dashboard Cite

BackgroundThe effect of rotavirus in developed countries is mainly economic. This study aimed to assess the indirect costs induced by rotavirus acute gastroenteritis (RVAGE) in Spain.MethodsA prospective observational study was conducted from October 2008 to June 2009. It included 682 children up to 5 years of age with acute gastroenteritis (AGE) who attended primary care (n = 18) and emergency room/hospital settings (n = 10), covering the regions of Galicia and Asturias (North-west Spain). All non-medical expenses incurred throughout the episode were recorded in detail using personal interviews and telephone contact.ResultsAmong the 682 enrolled children, 207 (30.4%) were rotavirus positive and 170 (25%) had received at least one dose of rotavirus vaccine. The mean (standard deviation) indirect cost caused by an episode of AGE was estimated at 135.17 (182.70) Euros. Costs were 1.74-fold higher when AGE was caused by rotavirus compared with other etiologies: 192.7 (219.8) Euros vs. 111.6 (163.5) Euros (p < .001). The costs for absenteeism were the most substantial with a mean of 91.41 (134.76) Euros per family, resulting in a loss of 2.45 (3.17) days of work. In RVAGE patients, the absenteeism cost was 120.4 (154) Euros compared with 75.8 (123) for the other etiologies (p = .002), because of loss of 3.5 (3.6) vs 1.9 (2.9) days of work (p < .001). Meals costs were 2-fold-higher (48.5 (55) vs 24.3 (46) Euros, p < .001) and travel costs were 2.6-fold-higher (32 (92) vs 12.5 (21.1) Euros, p = .005) in RVAGE patients compared with those with other etiologies. There were no differences between RVAGE and other etiologies groups regarding costs of hiring of caregivers or purchase of material. Patients with RVAGE were admitted to hospital more frequently than those with other etiologies (47.8% vs 14%, p < .001).ConclusionsRotavirus generates a significant indirect economic burden. Our data should be considered in the decision-making process of the eventual inclusion of rotavirus vaccine in the national immunization schedule of well developed countries.

show abstract

An estimation of indirect costs caused by acute rotavirus gastroenteritis in a Galician area, Spain

Cited by 18 publications

References 10 publications

Burden of paediatric Rotavirus Gastroenteritis (RVGE) and potential benefits of a universal Rotavirus vaccination programme with a pentavalent vaccine in Spain

Burden of paediatric Rotavirus Gastroenteritis (RVGE) and potential benefits of a universal Rotavirus vaccination programme with a pentavalent vaccine in Spain

Effectiveness of rotavirus vaccination in Spain

Prospective evaluation of indirect costs due to acute rotavirus gastroenteritis in Spain: the ROTACOST study

Contact Info

Product

Resources

About