Rotavirus A infections and reinfections: genotyping and vaccine implications

Abstract

The predominant G and P genotypes observed were similar to those found in new vaccines. No reinfection occurred during one-year of follow-up for any of the genotypes identified.

The burden of Rotavirus gastroenteritis among hospitalized pediatric patients in a tertiary referral hospital in Jeddah

“…The incidence of Rotavirus causing acute diarrhea ranged between 12 and 71%, with an average of 34% in children under 3 years of age. 17 The incidence was found to be between 5 and 71% in India, 12% to 42% in Brazil, 23.4% in Turkey, 24% in Zambia, 40% in Israel and 45.4% in Uganda in two studies done in 1987 and in 2010. 17 – 23 These results show that the burden of this disease has not changed over the years.…”

“… 17 The incidence was found to be between 5 and 71% in India, 12% to 42% in Brazil, 23.4% in Turkey, 24% in Zambia, 40% in Israel and 45.4% in Uganda in two studies done in 1987 and in 2010. 17 – 23 These results show that the burden of this disease has not changed over the years. It also shows that the incidence of RPG is similar in both developed and developing countries worldwide.…”

Molecular characterization of G1 human rotaviruses detected in children from Belém, Pará, Brazil

“…To date, at least 23 G and 30 P types have been identified based on sequence analysis of the VP7 and VP4 genes, respectively; however, few genotypes are known to 5,6,11,31,32 cause infection in humans . Although theoretically a high number of G/P combinations are possible, epidemiological studies worldwide have documented the circulation of five major types: G1P [8], G2P [4], G3P [8], 6,7,11,19,29 G4P [8] and G9P [8] .…”

Diversidade genética dos rotavírus humanos detectados em pacientes com diarréia aguda no Estado de São Paulo, no período de 1996 a 2006.

“…Poucos estudos sobre a ocorrência dos rotavírus têm sido realizados na região sul do País. Em Ponta Grossa, Paraná, Pietruchinski et al (2006) 1986a 2005(CARDOSO et al, 2003COSTA et al, 2004;MUNFORD et al, 2009).…”

“…Em Goiás, nos períodos de 1986 a 1995 e 2000 a 2003 observou-se da mesma forma o maior predomínio do G1 entre as amostras de RVs analisadas (CARDOSO et al, 2001;SOUZA et al, 2003;COSTA et al, 2004). Pietruchinski et al (2006) demonstraram em 2003 na cidade de Ponta Grossa,…”